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  5. Kfl00279_0130

Kfl00279_0130 (kfl00279_0130_v1.1)


Aliases : kfl00279_0130_v1.1

Description : (at4g30870 : 152.0) Encodes an Arabidopsis homolog of the endonuclease MSU81. T-DNA insertion lines of AtMSU81 have a deficiency in homologous recombination in somatic cells but only after genotoxic stress. Crosses with a hyperrecombinogenic mutant of the AtRecQ4A helicase resulted in synthetic lethality in the double mutant.; MMS AND UV SENSITIVE 81 (MUS81); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Restriction endonuclease, type II-like (InterPro:IPR011335); BEST Arabidopsis thaliana protein match is: Restriction endonuclease, type II-like superfamily protein (TAIR:AT5G39770.1); Has 631 Blast hits to 481 proteins in 192 species: Archae - 11; Bacteria - 4; Metazoa - 158; Fungi - 249; Plants - 48; Viruses - 0; Other Eukaryotes - 161 (source: NCBI BLink). & (reliability: 304.0) & (original description: no original description)


Gene families : OG_42_0005044 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005044_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00279_0130
Cluster HCCA clusters: Cluster_67

Target Alias Description ECC score Gene Family Method Actions
Cre12.g555050 No alias Restriction endonuclease, type II-like superfamily protein 0.02 Orthogroups_2024-Update
Glyma.11G150100 No alias Restriction endonuclease, type II-like superfamily protein 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0004518 nuclease activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Predicted GO
BP GO:0000098 sulfur amino acid catabolic process IEP Predicted GO
CC GO:0000151 ubiquitin ligase complex IEP Predicted GO
CC GO:0000152 nuclear ubiquitin ligase complex IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003689 DNA clamp loader activity IEP Predicted GO
MF GO:0003713 transcription coactivator activity IEP Predicted GO
MF GO:0003887 DNA-directed DNA polymerase activity IEP Predicted GO
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004222 metalloendopeptidase activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005663 DNA replication factor C complex IEP Predicted GO
CC GO:0005680 anaphase-promoting complex IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
CC GO:0005856 cytoskeleton IEP Predicted GO
CC GO:0005885 Arp2/3 protein complex IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
BP GO:0007015 actin filament organization IEP Predicted GO
BP GO:0008064 regulation of actin polymerization or depolymerization IEP Predicted GO
MF GO:0008094 DNA-dependent ATPase activity IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
BP GO:0009063 cellular amino acid catabolic process IEP Predicted GO
BP GO:0010638 positive regulation of organelle organization IEP Predicted GO
MF GO:0015399 primary active transmembrane transporter activity IEP Predicted GO
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity IEP Predicted GO
CC GO:0015629 actin cytoskeleton IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
BP GO:0016054 organic acid catabolic process IEP Predicted GO
BP GO:0016255 attachment of GPI anchor to protein IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
BP GO:0030328 prenylcysteine catabolic process IEP Predicted GO
BP GO:0030329 prenylcysteine metabolic process IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
BP GO:0030832 regulation of actin filament length IEP Predicted GO
BP GO:0030833 regulation of actin filament polymerization IEP Predicted GO
BP GO:0030838 positive regulation of actin filament polymerization IEP Predicted GO
BP GO:0031334 positive regulation of protein complex assembly IEP Predicted GO
CC GO:0031461 cullin-RING ubiquitin ligase complex IEP Predicted GO
MF GO:0031625 ubiquitin protein ligase binding IEP Predicted GO
BP GO:0032271 regulation of protein polymerization IEP Predicted GO
BP GO:0032273 positive regulation of protein polymerization IEP Predicted GO
BP GO:0032535 regulation of cellular component size IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0032956 regulation of actin cytoskeleton organization IEP Predicted GO
BP GO:0032970 regulation of actin filament-based process IEP Predicted GO
MF GO:0033170 protein-DNA loading ATPase activity IEP Predicted GO
BP GO:0034314 Arp2/3 complex-mediated actin nucleation IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042219 cellular modified amino acid catabolic process IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
MF GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEP Predicted GO
CC GO:0042765 GPI-anchor transamidase complex IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043254 regulation of protein complex assembly IEP Predicted GO
MF GO:0043492 ATPase activity, coupled to movement of substances IEP Predicted GO
BP GO:0044087 regulation of cellular component biogenesis IEP Predicted GO
BP GO:0044089 positive regulation of cellular component biogenesis IEP Predicted GO
BP GO:0044273 sulfur compound catabolic process IEP Predicted GO
MF GO:0044389 ubiquitin-like protein ligase binding IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044432 endoplasmic reticulum part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045010 actin nucleation IEP Predicted GO
BP GO:0046395 carboxylic acid catabolic process IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0051130 positive regulation of cellular component organization IEP Predicted GO
BP GO:0051276 chromosome organization IEP Predicted GO
BP GO:0051493 regulation of cytoskeleton organization IEP Predicted GO
BP GO:0051495 positive regulation of cytoskeleton organization IEP Predicted GO
MF GO:0070008 serine-type exopeptidase activity IEP Predicted GO
CC GO:0070531 BRCA1-A complex IEP Predicted GO
CC GO:0070552 BRISC complex IEP Predicted GO
BP GO:0090066 regulation of anatomical structure size IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
BP GO:0097435 supramolecular fiber organization IEP Predicted GO
BP GO:0110053 regulation of actin filament organization IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
CC GO:1902494 catalytic complex IEP Predicted GO
BP GO:1902903 regulation of supramolecular fiber organization IEP Predicted GO
BP GO:1902905 positive regulation of supramolecular fiber organization IEP Predicted GO
InterPro domains Description Start Stop
IPR006166 ERCC4_domain 546 676
No external refs found!