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GO:0003713: transcription coactivator activity (Molecular function)

"A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator." [GOC:txnOH-2018, PMID:10213677, PMID:16858867]


There are 2007 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_271 Solanum lycopersicum 2.04 % 0.010109 0.040094
Cluster_386 Solanum pennellii 1.56 % 0.007097 0.041267
Cluster_172 Pseudotsuga menziesii 1.14 % 0.002453 0.035461
Cluster_249 Brachypodium distachyon 1.82 % 0.006397 0.037582
Cluster_161 Nicotiana attenuata 1.12 % 0.005335 0.031502
Cluster_29 Nicotiana attenuata 0.71 % 0.008386 0.03
Cluster_12 Zea mays 0.85 % 0.000134 0.026595
Cluster_257 Setaria italica 2.0 % 0.001446 0.011917
Cluster_123 Marchantia polymorpha 1.72 % 0.005964 0.047352
Cluster_101 Marchantia polymorpha 1.49 % 0.006888 0.036909
Sequences (2007) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms