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  5. Kfl00285_0110

Kfl00285_0110 (kfl00285_0110_v1.1)


Aliases : kfl00285_0110_v1.1

Description : (at3g48190 : 1393.0) encodes a homolog of the human ATM gene, which is mutated in ataxia telangiectasia, a chromosome instability disorder. Characterization of mutants suggest a role in repairing DNA in response to ionizing radiation as well as during meiosis. The protein has kinase domains and shows kinase activity in orthologs. There is also evidence that ATM might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres.; ataxia-telangiectasia mutated (ATM); FUNCTIONS IN: 1-phosphatidylinositol-3-phosphate 5-kinase activity; INVOLVED IN: in 8 processes; LOCATED IN: chloroplast; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), PIK-related kinase, FAT (InterPro:IPR003151), Ataxia-Telangiectasia Mutated (InterPro:IPR015519), PIK-related kinase (InterPro:IPR014009), PWWP (InterPro:IPR000313), PIK-related kinase, FATC (InterPro:IPR003152), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 3479 Blast hits to 3364 proteins in 268 species: Archae - 0; Bacteria - 7; Metazoa - 1400; Fungi - 858; Plants - 531; Viruses - 0; Other Eukaryotes - 683 (source: NCBI BLink). & (q5z987|atr_orysa : 233.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (reliability: 2786.0) & (original description: no original description)


Gene families : OG_42_0006876 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006876_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00285_0110
Cluster HCCA clusters: Cluster_37

Target Alias Description ECC score Gene Family Method Actions
At3g48190 No alias Serine/Threonine-kinase ATM-like protein... 0.02 Orthogroups_2024-Update
Cre13.g564350 No alias ataxia-telangiectasia mutated 0.04 Orthogroups_2024-Update
LOC_Os01g01689 No alias phosphatidylinositol 3- and 4-kinase family protein, expressed 0.01 Orthogroups_2024-Update
Solyc03g112950 No alias Serine/Threonine-kinase ATM-like protein (AHRD V3.3 ***... 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003712 transcription coregulator activity IEP Predicted GO
MF GO:0004176 ATP-dependent peptidase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0004402 histone acetyltransferase activity IEP Predicted GO
MF GO:0004842 ubiquitin-protein transferase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005789 endoplasmic reticulum membrane IEP Predicted GO
BP GO:0006013 mannose metabolic process IEP Predicted GO
BP GO:0006473 protein acetylation IEP Predicted GO
BP GO:0006475 internal protein amino acid acetylation IEP Predicted GO
BP GO:0006606 protein import into nucleus IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0006914 autophagy IEP Predicted GO
MF GO:0008080 N-acetyltransferase activity IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
MF GO:0016307 phosphatidylinositol phosphate kinase activity IEP Predicted GO
MF GO:0016410 N-acyltransferase activity IEP Predicted GO
BP GO:0016573 histone acetylation IEP Predicted GO
BP GO:0016579 protein deubiquitination IEP Predicted GO
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
BP GO:0017038 protein import IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0018393 internal peptidyl-lysine acetylation IEP Predicted GO
BP GO:0018394 peptidyl-lysine acetylation IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
MF GO:0019787 ubiquitin-like protein transferase activity IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0032947 protein-containing complex scaffold activity IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
MF GO:0034212 peptide N-acetyltransferase activity IEP Predicted GO
BP GO:0034504 protein localization to nucleus IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043248 proteasome assembly IEP Predicted GO
BP GO:0043543 protein acylation IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051170 import into nucleus IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
MF GO:0051920 peroxiredoxin activity IEP Predicted GO
CC GO:0061695 transferase complex, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0061733 peptide-lysine-N-acetyltransferase activity IEP Predicted GO
BP GO:0061919 process utilizing autophagic mechanism IEP Predicted GO
BP GO:0070646 protein modification by small protein removal IEP Predicted GO
BP GO:0070647 protein modification by small protein conjugation or removal IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
CC GO:1902554 serine/threonine protein kinase complex IEP Predicted GO
CC GO:1902911 protein kinase complex IEP Predicted GO
CC GO:1990316 Atg1/ULK1 kinase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR000403 PI3/4_kinase_cat_dom 2726 2966
IPR003152 FATC_dom 3025 3054
IPR003151 PIK-rel_kinase_FAT 2104 2508
No external refs found!