Kfl00293_0030 (kfl00293_0030_v1.1)


Aliases : kfl00293_0030_v1.1

Description : (at5g64300 : 554.0) encodes GTP cyclohydrolase II that can functionally complement E. coli mutant deficient in this gene. It also has 3,4-dihydroxy-2-butanone-4-phosphate synthase activity which makes it a bifunctional enzyme involved in the formation of the pyrimidine and of the carbohydrate from GTP and ribulose-5-phosphate, respectively; GTP cyclohydrolase II (GCH); FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; LOCATED IN: chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: riboflavin biosynthesis protein, putative (TAIR:AT2G22450.1); Has 11690 Blast hits to 11688 proteins in 2324 species: Archae - 209; Bacteria - 6956; Metazoa - 1; Fungi - 397; Plants - 132; Viruses - 0; Other Eukaryotes - 3995 (source: NCBI BLink). & (reliability: 1108.0) & (original description: no original description)


Gene families : OG_42_0001532 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001532_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00293_0030
Cluster HCCA clusters: Cluster_48

Target Alias Description ECC score Gene Family Method Actions
At2g22450 No alias Monofunctional riboflavin biosynthesis protein RIBA 2,... 0.02 Orthogroups_2024-Update
Bradi3g38570 No alias GTP cyclohydrolase II 0.01 Orthogroups_2024-Update
Glyma.05G175500 No alias GTP cyclohydrolase II 0.03 Orthogroups_2024-Update
Glyma.08G132700 No alias GTP cyclohydrolase II 0.02 Orthogroups_2024-Update
MA_10426568g0010 No alias (at2g22450 : 295.0) riboflavin biosynthesis protein,... 0.02 Orthogroups_2024-Update
Sobic.004G187900.1 No alias bifunctional GTP cyclohydrolase II *(RibA) and DHBP... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity IEA InterProScan predictions
BP GO:0009231 riboflavin biosynthetic process IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004672 protein kinase activity IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0010207 photosystem II assembly IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0033743 peptide-methionine (R)-S-oxide reductase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR000422 DHBP_synthase_RibB 150 344
IPR032677 GTP_cyclohydro_II 356 520
No external refs found!