Kfl00312_0080 (kfl00312_0080_v1.1)


Aliases : kfl00312_0080_v1.1

Description : (at4g03560 : 413.0) Encodes a depolarization-activated Ca(2+) channel. Anti-sense experiments with this gene as well as Sucrose-H(+) symporters and complementation of yeast sucrose uptake mutant cch1 suggest that this protein mediates a voltage-activated Ca(2+ )influx. Mutants lack detectable SV channel activity suggesting TPC1 is essential component of the SV channel. Patch clamp analysis of loss of function mutation indicates TPC1 does not affect Ca2+ signaling in response to abiotic and biotic stress.; two-pore channel 1 (TPC1); FUNCTIONS IN: voltage-gated calcium channel activity, calcium channel activity; INVOLVED IN: regulation of jasmonic acid biosynthetic process, calcium ion transport, calcium-mediated signaling, seed germination, regulation of stomatal movement; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: EF-HAND 2 (InterPro:IPR018249), Ion transport (InterPro:IPR005821), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q5qm84|tpc1_orysa : 408.0) Probable voltage-dependent calcium channel protein TPC1 (Probable voltage-gated calcium channel) (Two-pore calcium channel protein) - Oryza sativa (Rice) & (reliability: 826.0) & (original description: no original description)


Gene families : OG_42_0003995 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003995_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00312_0080
Cluster HCCA clusters: Cluster_15

Target Alias Description ECC score Gene Family Method Actions
Brara.C02755.1 No alias voltage-gated calcium cation channel *(TPC) 0.01 Orthogroups_2024-Update
Brara.I00237.1 No alias voltage-gated calcium cation channel *(TPC) 0.02 Orthogroups_2024-Update
Glyma.12G204400 No alias two-pore channel 1 0.01 Orthogroups_2024-Update
Glyma.13G296900 No alias two-pore channel 1 0.02 Orthogroups_2024-Update
Pp1s258_30V6 No alias two-pore calcium channel 0.04 Orthogroups_2024-Update
evm.model.tig00021428.17 No alias no hits & (original description: no original description) 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005216 ion channel activity IEA InterProScan predictions
BP GO:0006811 ion transport IEA InterProScan predictions
CC GO:0016020 membrane IEA InterProScan predictions
BP GO:0055085 transmembrane transport IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000151 ubiquitin ligase complex IEP Predicted GO
MF GO:0001871 pattern binding IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006631 fatty acid metabolic process IEP Predicted GO
BP GO:0006633 fatty acid biosynthetic process IEP Predicted GO
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
MF GO:0030247 polysaccharide binding IEP Predicted GO
BP GO:0030259 lipid glycosylation IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
MF GO:0034450 ubiquitin-ubiquitin ligase activity IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0044255 cellular lipid metabolic process IEP Predicted GO
MF GO:0045300 acyl-[acyl-carrier-protein] desaturase activity IEP Predicted GO
MF GO:0061630 ubiquitin protein ligase activity IEP Predicted GO
MF GO:0061659 ubiquitin-like protein ligase activity IEP Predicted GO
MF GO:0070569 uridylyltransferase activity IEP Predicted GO
MF GO:2001070 starch binding IEP Predicted GO
InterPro domains Description Start Stop
IPR005821 Ion_trans_dom 451 690
IPR005821 Ion_trans_dom 128 326
No external refs found!