1. Home
  2. GO
  3. GO:0061630

GO:0061630: ubiquitin protein ligase activity (Molecular function)

"Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues." [GOC:BioGRID, GOC:dph, GOC:mah, GOC:tb, PMID:22863777]


There are 6466 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_369 Solanum pennellii 2.63 % 0.000253 0.02646
Cluster_76 Chlamydomonas reinhardtii 2.0 % 0.005629 0.032028
Cluster_147 Selaginella moellendorffii 1.2 % 0.003724 0.035711
Cluster_99 Zea mays 0.91 % 0.003373 0.023664
cluster_0008 Populus trichocarpa 0.93 % 0.004506 0.025347
Cluster_172 Sorghum bicolor 1.72 % 0.001015 0.031088
Cluster_352 Setaria italica 50.0 % 0.000867 0.006938
Cluster_114 Setaria italica 1.69 % 0.001177 0.011043
Cluster_321 Setaria italica 33.33 % 0.001301 0.007154
Sequences (6466) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !