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  5. Kfl00330_0070

Kfl00330_0070 (kfl00330_0070_v1.1)


Aliases : kfl00330_0070_v1.1

Description : (o23787|thi4_citsi : 475.0) Thiazole biosynthetic enzyme, chloroplast precursor - Citrus sinensis (Sweet orange) & (at5g54770 : 471.0) Encodes a thiamine biosynthetic gene that has a dual function in thiamine biosynthesis and mitochondrial DNA damage tolerance. It appears to be involved in producing the thiazole portion of thiamine (vitamin B1). A crystal structure of the protein reveals that it forms a 2-ring homo-octamer.; THI1; FUNCTIONS IN: protein homodimerization activity, zinc ion binding; INVOLVED IN: oxazole or thiazole biosynthetic process, response to cold, thiamin biosynthetic process, response to DNA damage stimulus; LOCATED IN: in 6 components; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thiamine biosynthesis Thi4 protein (InterPro:IPR002922); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 942.0) & (original description: no original description)


Gene families : OG_42_0004114 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004114_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Klebsormidium release: Kfl00330_0070
Cluster HCCA clusters: Cluster_18

Target Alias Description ECC score Gene Family Method Actions
Glyma.20G142000 No alias thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4) 0.01 Orthogroups_2024-Update
Potri.004G020500 No alias thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4) 0.01 Orthogroups_2024-Update
Pp1s16_179V6 No alias thiazole biosynthetic enzyme 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0000723 telomere maintenance IEP Predicted GO
BP GO:0000724 double-strand break repair via homologous recombination IEP Predicted GO
BP GO:0000725 recombinational repair IEP Predicted GO
CC GO:0000781 chromosome, telomeric region IEP Predicted GO
CC GO:0000784 nuclear chromosome, telomeric region IEP Predicted GO
CC GO:0000796 condensin complex IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0003887 DNA-directed DNA polymerase activity IEP Predicted GO
MF GO:0003896 DNA primase activity IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006260 DNA replication IEP Predicted GO
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006302 double-strand break repair IEP Predicted GO
BP GO:0006323 DNA packaging IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006401 RNA catabolic process IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006772 thiamine metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
BP GO:0007062 sister chromatid cohesion IEP Predicted GO
BP GO:0007064 mitotic sister chromatid cohesion IEP Predicted GO
BP GO:0007076 mitotic chromosome condensation IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009228 thiamine biosynthetic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEP Predicted GO
MF GO:0016597 amino acid binding IEP Predicted GO
MF GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016743 carboxyl- or carbamoyltransferase activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
BP GO:0022402 cell cycle process IEP Predicted GO
BP GO:0030261 chromosome condensation IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
CC GO:0031390 Ctf18 RFC-like complex IEP Predicted GO
MF GO:0031406 carboxylic acid binding IEP Predicted GO
BP GO:0032200 telomere organization IEP Predicted GO
CC GO:0032299 ribonuclease H2 complex IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
MF GO:0034061 DNA polymerase activity IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042723 thiamine-containing compound metabolic process IEP Predicted GO
BP GO:0042724 thiamine-containing compound biosynthetic process IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
MF GO:0043138 3'-5' DNA helicase activity IEP Predicted GO
MF GO:0043140 ATP-dependent 3'-5' DNA helicase activity IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
MF GO:0043177 organic acid binding IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044427 chromosomal part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044454 nuclear chromosome part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
CC GO:0044815 DNA packaging complex IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051276 chromosome organization IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
BP GO:0060249 anatomical structure homeostasis IEP Predicted GO
MF GO:0061731 ribonucleoside-diphosphate reductase activity IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
CC GO:0098687 chromosomal region IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1903047 mitotic cell cycle process IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!