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- Kfl00357_0080
Kfl00357_0080 (kfl00357_0080_v1.1)
Aliases : kfl00357_0080_v1.1
Description : (at1g09830 : 602.0) glycinamide ribonucleotide synthetase (GAR synthetase) that catalyzes the conversion of phosphoribosyl amine to phosphoribosyl glycineamide; Glycinamide ribonucleotide (GAR) synthetase; FUNCTIONS IN: phosphoribosylamine-glycine ligase activity; INVOLVED IN: purine base biosynthetic process, purine nucleotide biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribosylglycinamide synthetase, conserved site (InterPro:IPR020559), Phosphoribosylglycinamide synthetase, C-domain (InterPro:IPR020560), Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (InterPro:IPR020561), ATP-grasp fold, subdomain 1 (InterPro:IPR013815), PreATP-grasp-like fold (InterPro:IPR016185), Phosphoribosylglycinamide synthetase, N-domain (InterPro:IPR020562), ATP-grasp fold (InterPro:IPR011761), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Pre-ATP-grasp fold (InterPro:IPR013817), Rudiment single hybrid motif (InterPro:IPR011054), Phosphoribosylglycinamide synthetase (InterPro:IPR000115); Has 12648 Blast hits to 12644 proteins in 2666 species: Archae - 340; Bacteria - 7373; Metazoa - 216; Fungi - 226; Plants - 88; Viruses - 0; Other Eukaryotes - 4405 (source: NCBI BLink). & (p52421|pur2_vigun : 385.0) Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase) (Fragment) - Vigna unguiculata (Cowpea) & (reliability: 1204.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Klebsormidium release: Kfl00357_0080 | |
| Cluster | HCCA clusters: Cluster_69 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| Bradi4g21820 | No alias | Glycinamide ribonucleotide (GAR) synthetase | 0.02 | Orthogroups_2024-Update | |
| Brara.F00642.1 | No alias | glycinamide RN synthetase *(GARS) & EC_6.3 ligase... | 0.02 | Orthogroups_2024-Update | |
| PSME_00024268-RA | No alias | (at1g09830 : 372.0) glycinamide ribonucleotide... | 0.02 | Orthogroups_2024-Update | |
| Potri.004G225500 | No alias | Glycinamide ribonucleotide (GAR) synthetase | 0.01 | Orthogroups_2024-Update | |
| Seita.8G084700.1 | No alias | glycinamide RN synthetase *(GARS) & EC_6.3 ligase... | 0.02 | Orthogroups_2024-Update | |
| evm.model.tig00000194.21 | No alias | (at1g09830 : 392.0) glycinamide ribonucleotide... | 0.02 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0003824 | catalytic activity | None | Extended |
| MF | GO:0004637 | phosphoribosylamine-glycine ligase activity | IEA | InterProScan predictions |
| BP | GO:0006139 | nucleobase-containing compound metabolic process | None | Extended |
| BP | GO:0006144 | purine nucleobase metabolic process | None | Extended |
| BP | GO:0006725 | cellular aromatic compound metabolic process | None | Extended |
| BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
| BP | GO:0008150 | biological_process | None | Extended |
| BP | GO:0008152 | metabolic process | None | Extended |
| BP | GO:0009058 | biosynthetic process | None | Extended |
| BP | GO:0009112 | nucleobase metabolic process | None | Extended |
| BP | GO:0009113 | purine nucleobase biosynthetic process | IEA | InterProScan predictions |
| BP | GO:0009987 | cellular process | None | Extended |
| MF | GO:0016874 | ligase activity | None | Extended |
| MF | GO:0016879 | ligase activity, forming carbon-nitrogen bonds | None | Extended |
| BP | GO:0018130 | heterocycle biosynthetic process | None | Extended |
| BP | GO:0019438 | aromatic compound biosynthetic process | None | Extended |
| BP | GO:0034641 | cellular nitrogen compound metabolic process | None | Extended |
| BP | GO:0042440 | pigment metabolic process | None | Extended |
| BP | GO:0044237 | cellular metabolic process | None | Extended |
| BP | GO:0044238 | primary metabolic process | None | Extended |
| BP | GO:0044249 | cellular biosynthetic process | None | Extended |
| BP | GO:0044271 | cellular nitrogen compound biosynthetic process | None | Extended |
| BP | GO:0044281 | small molecule metabolic process | None | Extended |
| BP | GO:0046112 | nucleobase biosynthetic process | None | Extended |
| BP | GO:0046148 | pigment biosynthetic process | None | Extended |
| BP | GO:0046483 | heterocycle metabolic process | None | Extended |
| BP | GO:0055086 | nucleobase-containing small molecule metabolic process | None | Extended |
| BP | GO:0071704 | organic substance metabolic process | None | Extended |
| BP | GO:0072521 | purine-containing compound metabolic process | None | Extended |
| BP | GO:0072522 | purine-containing compound biosynthetic process | None | Extended |
| BP | GO:1901360 | organic cyclic compound metabolic process | None | Extended |
| BP | GO:1901362 | organic cyclic compound biosynthetic process | None | Extended |
| BP | GO:1901564 | organonitrogen compound metabolic process | None | Extended |
| BP | GO:1901566 | organonitrogen compound biosynthetic process | None | Extended |
| BP | GO:1901576 | organic substance biosynthetic process | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0002161 | aminoacyl-tRNA editing activity | IEP | Predicted GO |
| MF | GO:0003746 | translation elongation factor activity | IEP | Predicted GO |
| MF | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity | IEP | Predicted GO |
| MF | GO:0004518 | nuclease activity | IEP | Predicted GO |
| MF | GO:0004540 | ribonuclease activity | IEP | Predicted GO |
| BP | GO:0006072 | glycerol-3-phosphate metabolic process | IEP | Predicted GO |
| BP | GO:0006414 | translational elongation | IEP | Predicted GO |
| BP | GO:0006771 | riboflavin metabolic process | IEP | Predicted GO |
| MF | GO:0008483 | transaminase activity | IEP | Predicted GO |
| BP | GO:0009231 | riboflavin biosynthetic process | IEP | Predicted GO |
| CC | GO:0009349 | riboflavin synthase complex | IEP | Predicted GO |
| BP | GO:0016070 | RNA metabolic process | IEP | Predicted GO |
| BP | GO:0016458 | gene silencing | IEP | Predicted GO |
| MF | GO:0016769 | transferase activity, transferring nitrogenous groups | IEP | Predicted GO |
| MF | GO:0016788 | hydrolase activity, acting on ester bonds | IEP | Predicted GO |
| BP | GO:0022613 | ribonucleoprotein complex biogenesis | IEP | Predicted GO |
| BP | GO:0031047 | gene silencing by RNA | IEP | Predicted GO |
| BP | GO:0042254 | ribosome biogenesis | IEP | Predicted GO |
| BP | GO:0042726 | flavin-containing compound metabolic process | IEP | Predicted GO |
| BP | GO:0042727 | flavin-containing compound biosynthetic process | IEP | Predicted GO |
| BP | GO:0046168 | glycerol-3-phosphate catabolic process | IEP | Predicted GO |
| MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
| MF | GO:0051539 | 4 iron, 4 sulfur cluster binding | IEP | Predicted GO |
| BP | GO:0052646 | alditol phosphate metabolic process | IEP | Predicted GO |
| MF | GO:0052689 | carboxylic ester hydrolase activity | IEP | Predicted GO |
| MF | GO:0070567 | cytidylyltransferase activity | IEP | Predicted GO |
| MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
| MF | GO:0140101 | catalytic activity, acting on a tRNA | IEP | Predicted GO |
| BP | GO:1901136 | carbohydrate derivative catabolic process | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR020562 | PRibGlycinamide_synth_N | 34 | 136 |
| IPR020560 | PRibGlycinamide_synth_C-dom | 367 | 460 |
| IPR020561 | PRibGlycinamid_synth_ATP-grasp | 137 | 331 |
