1. Home
  2. Species
  3. Klebsormidium nitens
  4. Sequence
  5. Kfl00523_0070

Kfl00523_0070 (kfl00523_0070_v1.1)


Aliases : kfl00523_0070_v1.1

Description : (at5g58230 : 676.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1352.0) & (original description: no original description)


Gene families : OG_42_0002428 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002428_tree

Sequence : coding (download), protein (download)


Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00523_0070
Cluster HCCA clusters: Cluster_18

Target Alias Description ECC score Gene Family Method Actions
233646 No alias Transducin/WD40 repeat-like superfamily protein 0.02 Orthogroups_2024-Update
A4A49_07762 No alias wd-40 repeat-containing protein msi2 0.01 Orthogroups_2024-Update
At2g16780 No alias WD-40 repeat-containing protein MSI2... 0.02 Orthogroups_2024-Update
Bradi4g36580 No alias Transducin/WD40 repeat-like superfamily protein 0.01 Orthogroups_2024-Update
Brara.G00312.1 No alias component *(CAF1c/MSI) of CAF1 histone chaperone complex... 0.02 Orthogroups_2024-Update
Cre12.g523200 No alias Transducin/WD40 repeat-like superfamily protein 0.03 Orthogroups_2024-Update
Glyma.08G085900 No alias Transducin/WD40 repeat-like superfamily protein 0.02 Orthogroups_2024-Update
Seita.2G291200.1 No alias component *(CAF1c/MSI) of CAF1 histone chaperone complex... 0.03 Orthogroups_2024-Update
Seita.9G159200.1 No alias component *(MSI1) of PRC2 histone methylation complex &... 0.03 Orthogroups_2024-Update
Solyc01g111590 No alias Transducin family protein / WD-40 repeat family protein... 0.04 Orthogroups_2024-Update
evm.model.contig_4455.3 No alias (at5g58230 : 470.0) Encodes a WD-40 repeat containing... 0.02 Orthogroups_2024-Update
evm.model.tig00000808.15 No alias (at5g58230 : 455.0) Encodes a WD-40 repeat containing... 0.05 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Toggle parental
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0000278 mitotic cell cycle IEP Predicted GO
BP GO:0000723 telomere maintenance IEP Predicted GO
CC GO:0000775 chromosome, centromeric region IEP Predicted GO
CC GO:0000781 chromosome, telomeric region IEP Predicted GO
CC GO:0000784 nuclear chromosome, telomeric region IEP Predicted GO
CC GO:0000808 origin recognition complex IEP Predicted GO
MF GO:0002161 aminoacyl-tRNA editing activity IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003855 3-dehydroquinate dehydratase activity IEP Predicted GO
MF GO:0003887 DNA-directed DNA polymerase activity IEP Predicted GO
MF GO:0003896 DNA primase activity IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0003924 GTPase activity IEP Predicted GO
MF GO:0004146 dihydrofolate reductase activity IEP Predicted GO
MF GO:0004470 malic enzyme activity IEP Predicted GO
MF GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEP Predicted GO
MF GO:0004764 shikimate 3-dehydrogenase (NADP+) activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006260 DNA replication IEP Predicted GO
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Predicted GO
BP GO:0006270 DNA replication initiation IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006298 mismatch repair IEP Predicted GO
BP GO:0006302 double-strand break repair IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006760 folic acid-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006891 intra-Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
BP GO:0007049 cell cycle IEP Predicted GO
BP GO:0007062 sister chromatid cohesion IEP Predicted GO
BP GO:0007064 mitotic sister chromatid cohesion IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009163 nucleoside biosynthetic process IEP Predicted GO
BP GO:0009396 folic acid-containing compound biosynthetic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010639 negative regulation of organelle organization IEP Predicted GO
MF GO:0016597 amino acid binding IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016615 malate dehydrogenase activity IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Predicted GO
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016743 carboxyl- or carbamoyltransferase activity IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
CC GO:0017119 Golgi transport complex IEP Predicted GO
CC GO:0019867 outer membrane IEP Predicted GO
MF GO:0030145 manganese ion binding IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
CC GO:0031390 Ctf18 RFC-like complex IEP Predicted GO
MF GO:0031406 carboxylic acid binding IEP Predicted GO
BP GO:0032200 telomere organization IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033044 regulation of chromosome organization IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
MF GO:0034061 DNA polymerase activity IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042278 purine nucleoside metabolic process IEP Predicted GO
BP GO:0042451 purine nucleoside biosynthetic process IEP Predicted GO
BP GO:0042455 ribonucleoside biosynthetic process IEP Predicted GO
CC GO:0042555 MCM complex IEP Predicted GO
BP GO:0042558 pteridine-containing compound metabolic process IEP Predicted GO
BP GO:0042559 pteridine-containing compound biosynthetic process IEP Predicted GO
BP GO:0043086 negative regulation of catalytic activity IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
MF GO:0043177 organic acid binding IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0044092 negative regulation of molecular function IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044427 chromosomal part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046128 purine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046129 purine ribonucleoside biosynthetic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046653 tetrahydrofolate metabolic process IEP Predicted GO
BP GO:0046654 tetrahydrofolate biosynthetic process IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051095 regulation of helicase activity IEP Predicted GO
BP GO:0051097 negative regulation of helicase activity IEP Predicted GO
BP GO:0051129 negative regulation of cellular component organization IEP Predicted GO
BP GO:0051276 chromosome organization IEP Predicted GO
BP GO:0051336 regulation of hydrolase activity IEP Predicted GO
BP GO:0051346 negative regulation of hydrolase activity IEP Predicted GO
MF GO:0051499 D-aminoacyl-tRNA deacylase activity IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
BP GO:0060249 anatomical structure homeostasis IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
CC GO:0098687 chromosomal region IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901659 glycosyl compound biosynthetic process IEP Predicted GO
BP GO:1903047 mitotic cell cycle process IEP Predicted GO
BP GO:1905462 regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905463 negative regulation of DNA duplex unwinding IEP Predicted GO
BP GO:1905774 regulation of DNA helicase activity IEP Predicted GO
BP GO:1905775 negative regulation of DNA helicase activity IEP Predicted GO
BP GO:2001251 negative regulation of chromosome organization IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 265 302
IPR001680 WD40_repeat 309 347
IPR001680 WD40_repeat 222 257
IPR001680 WD40_repeat 368 403
IPR022052 Histone-bd_RBBP4_N 19 88
No external refs found!