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  5. Kfl00591_0110

Kfl00591_0110 (kfl00591_0110_v1.1)


Aliases : kfl00591_0110_v1.1

Description : (at1g78870 : 291.0) UBC35/UBC13A encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UBC35/UBC13A can form diubiquitin and triubiquitin chains in combination with MMZ1,2,3,4/(UEV1A,B,C,D) in vitro. It can also functionally complement an mms2 ubc13 mutation in budding yeast by increasing the double mutant's viability in the presence of the DNA damaging agent MMS, when it is co-expressed with MMZ / UEV1 genes. A wild type phenotype is restored with MMZ3/UEV1C and MMZ4/UEV1D, but only partial complementation is achieved with MMZ1/UEV1A or MMZ2/UEV1B.; ubiquitin-conjugating enzyme 35 (UBC35); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: root epidermal cell differentiation, response to cadmium ion, postreplication repair, response to iron ion, ubiquitin-dependent protein catabolic process; LOCATED IN: UBC13-MMS2 complex; EXPRESSED IN: male gametophyte, cultured cell, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin-conjugating enzyme 36 (TAIR:AT1G16890.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (p25866|ubc2_wheat : 127.0) Ubiquitin-conjugating enzyme E2-17 kDa (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) - Triticum aestivum (Wheat) & (reliability: 582.0) & (original description: no original description)


Gene families : OG_42_0002519 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002519_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Klebsormidium release: Kfl00591_0110
Cluster HCCA clusters: Cluster_89

Target Alias Description ECC score Gene Family Method Actions
HORVU5Hr1G055360.2 No alias E2 ubiquitin-conjugating enzyme 0.02 Orthogroups_2024-Update
evm.model.tig00020629.95 No alias (at1g78870 : 211.0) UBC35/UBC13A encodes a protein that... 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
CC GO:0000439 transcription factor TFIIH core complex IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004721 phosphoprotein phosphatase activity IEP Predicted GO
MF GO:0005319 lipid transporter activity IEP Predicted GO
MF GO:0005548 phospholipid transporter activity IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005667 transcription factor complex IEP Predicted GO
CC GO:0005787 signal peptidase complex IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006289 nucleotide-excision repair IEP Predicted GO
BP GO:0006397 mRNA processing IEP Predicted GO
BP GO:0006465 signal peptide processing IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006631 fatty acid metabolic process IEP Predicted GO
BP GO:0006633 fatty acid biosynthetic process IEP Predicted GO
BP GO:0006869 lipid transport IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0015711 organic anion transport IEP Predicted GO
BP GO:0015748 organophosphate ester transport IEP Predicted GO
BP GO:0015914 phospholipid transport IEP Predicted GO
BP GO:0016485 protein processing IEP Predicted GO
MF GO:0016831 carboxy-lyase activity IEP Predicted GO
CC GO:0019773 proteasome core complex, alpha-subunit complex IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044432 endoplasmic reticulum part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
CC GO:0044798 nuclear transcription factor complex IEP Predicted GO
MF GO:0050080 malonyl-CoA decarboxylase activity IEP Predicted GO
BP GO:0051604 protein maturation IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
CC GO:0090575 RNA polymerase II transcription factor complex IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
CC GO:1905368 peptidase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR000608 UBQ-conjugat_E2 11 146
No external refs found!