Kfl00891_0050 (kfl00891_0050_v1.1)

Aliases : kfl00891_0050_v1.1

Description : (p39867|nia1_brana : 986.0) Nitrate reductase [NADH], clone PBNBR1405 (EC 1.7.1.1) (NR) - Brassica napus (Rape) & (at1g77760 : 974.0) Encodes the cytosolic minor isoform of nitrate reductase (NR). Involved in the first step of nitrate assimilation, it contributes about 15% of the nitrate reductase activity in shoots. Similar to molybdopterin oxidoreductases at the N-terminus, and to FAD/NAD-binding cytochrome reductases at the C-terminus. Cofactors: FAD, heme iron (cytochrome B-557), and molybdenum-pterin.; nitrate reductase 1 (NIA1); FUNCTIONS IN: nitrate reductase activity, protein binding; INVOLVED IN: nitric oxide biosynthetic process, nitrate assimilation, response to light stimulus; LOCATED IN: cytosol; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome b5, heme-binding site (InterPro:IPR018506), Nitrate reductase NADH dependent (InterPro:IPR012137), Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Oxidoreductase, FAD-binding domain (InterPro:IPR008333), Immunoglobulin E-set (InterPro:IPR014756), Cytochrome b5 (InterPro:IPR001199), NADH:cytochrome b5 reductase (CBR) (InterPro:IPR001834), Oxidoreductase, molybdopterin-binding domain (InterPro:IPR000572), Oxidoreductase FAD/NAD(P)-binding (InterPro:IPR001433), Oxidoreductase, molybdopterin binding site (InterPro:IPR022407), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Eukaryotic molybdopterin oxidoreductase (InterPro:IPR008335), Flavoprotein pyridine nucleotide cytochrome reductase (InterPro:IPR001709), Moybdenum cofactor oxidoreductase, dimerisation (InterPro:IPR005066); BEST Arabidopsis thaliana protein match is: nitrate reductase 2 (TAIR:AT1G37130.1); Has 14813 Blast hits to 14437 proteins in 2198 species: Archae - 168; Bacteria - 6976; Metazoa - 1728; Fungi - 2215; Plants - 1479; Viruses - 3; Other Eukaryotes - 2244 (source: NCBI BLink). & (reliability: 1948.0) & (original description: no original description)

Gene families : OG_42_0002591 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002591_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00891_0050
Cluster	HCCA clusters: Cluster_5

Target	Alias	Description	ECC score	Gene Family Method
GRMZM2G076723	No alias	nitrate reductase 1	0.02	Orthogroups_2024-Update
GRMZM2G568636	No alias	nitrate reductase 1	0.02	Orthogroups_2024-Update
HORVU6Hr1G003300.1	No alias	EC_1.7 oxidoreductase acting on other nitrogenous...	0.02	Orthogroups_2024-Update
LOC_Os08g36500	No alias	nitrate reductase, putative, expressed	0.02	Orthogroups_2024-Update
MA_16402g0010	No alias	(p39866\|nia2_phavu : 985.0) Nitrate reductase [NADH] 2...	0.03	Orthogroups_2024-Update
Mp2g10860.1	No alias	nitrate reductase	0.03	Orthogroups_2024-Update
evm.model.contig_2190.2	No alias	(p16081\|nia1_orysa : 776.0) Nitrate reductase [NADH] 1...	0.02	Orthogroups_2024-Update
evm.model.tig00001177.10	No alias	(p39867\|nia1_brana : 574.0) Nitrate reductase [NADH],...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	InterProScan predictions
MF	GO:0030151	molybdenum ion binding	IEA	InterProScan predictions
BP	GO:0042126	nitrate metabolic process	None	Extended
BP	GO:0042128	nitrate assimilation	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071941	nitrogen cycle metabolic process	None	Extended
BP	GO:2001057	reactive nitrogen species metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001101	response to acid chemical	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004345	glucose-6-phosphate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004359	glutaminase activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
BP	GO:0006006	glucose metabolic process	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006732	coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006777	Mo-molybdopterin cofactor biosynthetic process	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
MF	GO:0008113	peptide-methionine (S)-S-oxide reductase activity	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008987	quinolinate synthetase A activity	IEP	Predicted GO
BP	GO:0009108	coenzyme biosynthetic process	IEP	Predicted GO
BP	GO:0009435	NAD biosynthetic process	IEP	Predicted GO
BP	GO:0010035	response to inorganic substance	IEP	Predicted GO
BP	GO:0010167	response to nitrate	IEP	Predicted GO
BP	GO:0015706	nitrate transport	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
CC	GO:0019008	molybdopterin synthase complex	IEP	Predicted GO
BP	GO:0019637	organophosphate metabolic process	IEP	Predicted GO
BP	GO:0019674	NAD metabolic process	IEP	Predicted GO
BP	GO:0019720	Mo-molybdopterin cofactor metabolic process	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
MF	GO:0031072	heat shock protein binding	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0035091	phosphatidylinositol binding	IEP	Predicted GO
BP	GO:0042816	vitamin B6 metabolic process	IEP	Predicted GO
BP	GO:0042819	vitamin B6 biosynthetic process	IEP	Predicted GO
BP	GO:0042822	pyridoxal phosphate metabolic process	IEP	Predicted GO
BP	GO:0042823	pyridoxal phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0043545	molybdopterin cofactor metabolic process	IEP	Predicted GO
BP	GO:0046184	aldehyde biosynthetic process	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051186	cofactor metabolic process	IEP	Predicted GO
BP	GO:0051188	cofactor biosynthetic process	IEP	Predicted GO
BP	GO:0051189	prosthetic group metabolic process	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
MF	GO:0051536	iron-sulfur cluster binding	IEP	Predicted GO
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Predicted GO
MF	GO:0051540	metal cluster binding	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901617	organic hydroxy compound biosynthetic process	IEP	Predicted GO
BP	GO:1901698	response to nitrogen compound	IEP	Predicted GO
BP	GO:1901700	response to oxygen-containing compound	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000572	OxRdtase_Mopterin-bd_dom	124	302
IPR005066	MoCF_OxRdtse_dimer	331	458
IPR008333	Cbr1-like_FAD-bd_dom	643	749
IPR001199	Cyt_B5-like_heme/steroid-bd	524	594
IPR001433	OxRdtase_FAD/NAD-bd	769	876

External Links

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Kfl00891_0050 (kfl00891_0050_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation