Description : (at5g04620 : 255.0) The cDNA encoding 7-keto-8-aminopelargonic acid (KAPA) synthase, the first committed enzyme of the biotin synthesis pathway has been cloned and its molecular function confirmed (functional complementation of an E. coli mutant). The subcellular localization of the enzyme (cytosol) proves that the biotin biosynthesis in plants takes place in different compartments which differs from the biosynthetic route found in microorganisms.; biotin F (BIOF); CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: long chain base2 (TAIR:AT5G23670.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 510.0) & (original description: no original description)
Gene families : OG_42_0004149 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004149_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_103379g0010 | |
Cluster | HCCA clusters: Cluster_95 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
At5g04620 | No alias | 8-amino-7-oxononanoate synthase... | 0.03 | Orthogroups_2024-Update | |
Mp4g11260.1 | No alias | 7-keto-8-aminopelargonic acid (KAPA) synthase | 0.01 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0009058 | biosynthetic process | IEA | InterProScan predictions |
MF | GO:0030170 | pyridoxal phosphate binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0015399 | primary active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0042623 | ATPase activity, coupled | IEP | Predicted GO |
MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEP | Predicted GO |
MF | GO:0043492 | ATPase activity, coupled to movement of substances | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR004839 | Aminotransferase_I/II | 135 | 287 |
No external refs found! |