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  5. MA_10425800g0010

MA_10425800g0010


Description : (at1g54690 : 112.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (p50567|h2a_chlre : 112.0) Histone H2A - Chlamydomonas reinhardtii & (reliability: 224.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Picea release: MA_10425800g0010
Cluster HCCA clusters: Cluster_179

Target Alias Description ECC score Gene Family Method Actions
A4A49_56752 No alias putative histone h2a.1 0.03 Orthogroups_2024-Update
Glyma.12G215600 No alias histone H2A 2 0.02 Orthogroups_2024-Update
PSME_00017670-RA No alias (p35063|h2ax_picab : 188.0) Histone H2AX - Picea abies... 0.05 Orthogroups_2024-Update
PSME_00033712-RA No alias (q75l11|h2a6_orysa : 158.0) Probable histone H2A.6 -... 0.05 Orthogroups_2024-Update
Solyc03g005220 No alias calcium-dependent protein kinase 21 (AHRD V3.3 --* AT4G04720.2) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0003774 motor activity IEP Predicted GO
MF GO:0003777 microtubule motor activity IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
BP GO:0006486 protein glycosylation IEP Predicted GO
BP GO:0006928 movement of cell or subcellular component IEP Predicted GO
BP GO:0007017 microtubule-based process IEP Predicted GO
BP GO:0007018 microtubule-based movement IEP Predicted GO
MF GO:0008017 microtubule binding IEP Predicted GO
MF GO:0008373 sialyltransferase activity IEP Predicted GO
MF GO:0015631 tubulin binding IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0043413 macromolecule glycosylation IEP Predicted GO
BP GO:0070085 glycosylation IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
InterPro domains Description Start Stop
IPR007125 Histone_H2A/H2B/H3 18 96
IPR032454 Histone_H2A_C 99 132
No external refs found!