MA_10426943g0010


Description : (p50567|h2a_chlre : 132.0) Histone H2A - Chlamydomonas reinhardtii & (at1g08880 : 127.0) Encodes HTA5, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; H2AXA; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: gamma histone variant H2AX (TAIR:AT1G54690.1); Has 3916 Blast hits to 3911 proteins in 363 species: Archae - 0; Bacteria - 0; Metazoa - 2550; Fungi - 318; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 254.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_10426943g0010
Cluster HCCA clusters: Cluster_162

Target Alias Description ECC score Gene Family Method Actions
Cre06.g264950 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre06.g265350 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre06.g268050 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre06.g268300 No alias histone H2A 10 0.05 Orthogroups_2024-Update
Cre06.g274200 No alias histone H2A 10 0.04 Orthogroups_2024-Update
Cre06.g275850 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre12.g505550 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre12.g506250 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre13.g570100 No alias histone H2A 10 0.06 Orthogroups_2024-Update
Cre17.g708550 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Cre17.g709200 No alias histone H2A 10 0.03 Orthogroups_2024-Update
Cre17.g711700 No alias histone H2A 10 0.04 Orthogroups_2024-Update
Cre17.g713400 No alias histone H2A 10 0.02 Orthogroups_2024-Update
Glyma.13G333900 No alias histone H2A 12 0.03 Orthogroups_2024-Update
Glyma.15G040400 No alias histone H2A 12 0.03 Orthogroups_2024-Update
HORVU4Hr1G090910.2 No alias histone *(H2A) 0.05 Orthogroups_2024-Update
Kfl00099_g21 kfl00099_g21_v1.1 (q2qpg9|h2axb_orysa : 166.0) Probable histone H2AXb -... 0.02 Orthogroups_2024-Update
Kfl00125_0190 kfl00125_0190_v1.1 (p50567|h2a_chlre : 169.0) Histone H2A - Chlamydomonas... 0.01 Orthogroups_2024-Update
MA_10434390g0010 No alias (at5g54640 : 110.0) Isolated from T-DNA insertion line,... 0.03 Orthogroups_2024-Update
MA_924620g0010 No alias (q2hu68|h2a1_medtr : 180.0) Probable histone H2A.1 -... 0.02 Orthogroups_2024-Update
PSME_00000143-RA No alias (q84nj4|h2a3_orysa : 176.0) Probable histone H2A.3 -... 0.03 Orthogroups_2024-Update
PSME_00008207-RA No alias (p02276|h2a2_wheat : 135.0) Histone H2A.2.1 - Triticum... 0.05 Orthogroups_2024-Update
PSME_00008212-RA No alias (p50567|h2a_chlre : 107.0) Histone H2A - Chlamydomonas... 0.04 Orthogroups_2024-Update
PSME_00015855-RA No alias (at5g54640 : 145.0) Isolated from T-DNA insertion line,... 0.05 Orthogroups_2024-Update
PSME_00049247-RA No alias (p50567|h2a_chlre : 114.0) Histone H2A - Chlamydomonas... 0.04 Orthogroups_2024-Update
Pp1s72_86V6 No alias histone h2a 0.03 Orthogroups_2024-Update
Seita.5G370700.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
Sobic.001G416900.1 No alias histone *(H2A) 0.04 Orthogroups_2024-Update
Solyc01g099410 No alias Histone H2A (AHRD V3.3 *** G8IIJ5_SOLLC) 0.03 Orthogroups_2024-Update
Sopen09g031570 No alias Core histone H2A/H2B/H3/H4 0.03 Orthogroups_2024-Update
Sopen10g002510 No alias Core histone H2A/H2B/H3/H4 0.03 Orthogroups_2024-Update
evm.model.contig_533.4 No alias (p16866|h2a4_volca : 182.0) Histone H2A-IV - Volvox... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IEP Predicted GO
BP GO:0001932 regulation of protein phosphorylation IEP Predicted GO
CC GO:0005576 extracellular region IEP Predicted GO
CC GO:0005618 cell wall IEP Predicted GO
MF GO:0008171 O-methyltransferase activity IEP Predicted GO
BP GO:0010215 cellulose microfibril organization IEP Predicted GO
BP GO:0016049 cell growth IEP Predicted GO
MF GO:0016762 xyloglucan:xyloglucosyl transferase activity IEP Predicted GO
BP GO:0019220 regulation of phosphate metabolic process IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
MF GO:0019900 kinase binding IEP Predicted GO
MF GO:0019901 protein kinase binding IEP Predicted GO
BP GO:0030198 extracellular matrix organization IEP Predicted GO
CC GO:0030312 external encapsulating structure IEP Predicted GO
CC GO:0031225 anchored component of membrane IEP Predicted GO
BP GO:0031399 regulation of protein modification process IEP Predicted GO
BP GO:0032268 regulation of cellular protein metabolic process IEP Predicted GO
BP GO:0040007 growth IEP Predicted GO
BP GO:0042325 regulation of phosphorylation IEP Predicted GO
BP GO:0043062 extracellular structure organization IEP Predicted GO
BP GO:0043549 regulation of kinase activity IEP Predicted GO
BP GO:0045859 regulation of protein kinase activity IEP Predicted GO
CC GO:0048046 apoplast IEP Predicted GO
BP GO:0050790 regulation of catalytic activity IEP Predicted GO
BP GO:0051174 regulation of phosphorus metabolic process IEP Predicted GO
BP GO:0051246 regulation of protein metabolic process IEP Predicted GO
BP GO:0051338 regulation of transferase activity IEP Predicted GO
BP GO:0051726 regulation of cell cycle IEP Predicted GO
BP GO:0065009 regulation of molecular function IEP Predicted GO
BP GO:0071900 regulation of protein serine/threonine kinase activity IEP Predicted GO
BP GO:1904029 regulation of cyclin-dependent protein kinase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR032454 Histone_H2A_C 47 66
IPR032454 Histone_H2A_C 184 217
IPR007125 Histone_H2A/H2B/H3 71 181
No external refs found!