Description : (p50567|h2a_chlre : 132.0) Histone H2A - Chlamydomonas reinhardtii & (at1g08880 : 127.0) Encodes HTA5, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; H2AXA; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: gamma histone variant H2AX (TAIR:AT1G54690.1); Has 3916 Blast hits to 3911 proteins in 363 species: Archae - 0; Bacteria - 0; Metazoa - 2550; Fungi - 318; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 254.0) & (original description: no original description)
Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_10426943g0010 | |
Cluster | HCCA clusters: Cluster_162 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Cre06.g264950 | No alias | histone H2A 10 | 0.03 | Orthogroups_2024-Update | |
Cre06.g265350 | No alias | histone H2A 10 | 0.03 | Orthogroups_2024-Update | |
Cre06.g268050 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Cre06.g268300 | No alias | histone H2A 10 | 0.05 | Orthogroups_2024-Update | |
Cre06.g274200 | No alias | histone H2A 10 | 0.04 | Orthogroups_2024-Update | |
Cre06.g275850 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Cre12.g505550 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Cre12.g506250 | No alias | histone H2A 10 | 0.03 | Orthogroups_2024-Update | |
Cre13.g570100 | No alias | histone H2A 10 | 0.06 | Orthogroups_2024-Update | |
Cre17.g708550 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Cre17.g709200 | No alias | histone H2A 10 | 0.03 | Orthogroups_2024-Update | |
Cre17.g711700 | No alias | histone H2A 10 | 0.04 | Orthogroups_2024-Update | |
Cre17.g713400 | No alias | histone H2A 10 | 0.02 | Orthogroups_2024-Update | |
Glyma.13G333900 | No alias | histone H2A 12 | 0.03 | Orthogroups_2024-Update | |
Glyma.15G040400 | No alias | histone H2A 12 | 0.03 | Orthogroups_2024-Update | |
HORVU4Hr1G090910.2 | No alias | histone *(H2A) | 0.05 | Orthogroups_2024-Update | |
Kfl00099_g21 | kfl00099_g21_v1.1 | (q2qpg9|h2axb_orysa : 166.0) Probable histone H2AXb -... | 0.02 | Orthogroups_2024-Update | |
Kfl00125_0190 | kfl00125_0190_v1.1 | (p50567|h2a_chlre : 169.0) Histone H2A - Chlamydomonas... | 0.01 | Orthogroups_2024-Update | |
MA_10434390g0010 | No alias | (at5g54640 : 110.0) Isolated from T-DNA insertion line,... | 0.03 | Orthogroups_2024-Update | |
MA_924620g0010 | No alias | (q2hu68|h2a1_medtr : 180.0) Probable histone H2A.1 -... | 0.02 | Orthogroups_2024-Update | |
PSME_00000143-RA | No alias | (q84nj4|h2a3_orysa : 176.0) Probable histone H2A.3 -... | 0.03 | Orthogroups_2024-Update | |
PSME_00008207-RA | No alias | (p02276|h2a2_wheat : 135.0) Histone H2A.2.1 - Triticum... | 0.05 | Orthogroups_2024-Update | |
PSME_00008212-RA | No alias | (p50567|h2a_chlre : 107.0) Histone H2A - Chlamydomonas... | 0.04 | Orthogroups_2024-Update | |
PSME_00015855-RA | No alias | (at5g54640 : 145.0) Isolated from T-DNA insertion line,... | 0.05 | Orthogroups_2024-Update | |
PSME_00049247-RA | No alias | (p50567|h2a_chlre : 114.0) Histone H2A - Chlamydomonas... | 0.04 | Orthogroups_2024-Update | |
Pp1s72_86V6 | No alias | histone h2a | 0.03 | Orthogroups_2024-Update | |
Seita.5G370700.1 | No alias | histone *(H2A) | 0.03 | Orthogroups_2024-Update | |
Sobic.001G416900.1 | No alias | histone *(H2A) | 0.04 | Orthogroups_2024-Update | |
Solyc01g099410 | No alias | Histone H2A (AHRD V3.3 *** G8IIJ5_SOLLC) | 0.03 | Orthogroups_2024-Update | |
Sopen09g031570 | No alias | Core histone H2A/H2B/H3/H4 | 0.03 | Orthogroups_2024-Update | |
Sopen10g002510 | No alias | Core histone H2A/H2B/H3/H4 | 0.03 | Orthogroups_2024-Update | |
evm.model.contig_533.4 | No alias | (p16866|h2a4_volca : 182.0) Histone H2A-IV - Volvox... | 0.01 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000786 | nucleosome | IEA | InterProScan predictions |
MF | GO:0003677 | DNA binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | IEP | Predicted GO |
BP | GO:0001932 | regulation of protein phosphorylation | IEP | Predicted GO |
CC | GO:0005576 | extracellular region | IEP | Predicted GO |
CC | GO:0005618 | cell wall | IEP | Predicted GO |
MF | GO:0008171 | O-methyltransferase activity | IEP | Predicted GO |
BP | GO:0010215 | cellulose microfibril organization | IEP | Predicted GO |
BP | GO:0016049 | cell growth | IEP | Predicted GO |
MF | GO:0016762 | xyloglucan:xyloglucosyl transferase activity | IEP | Predicted GO |
BP | GO:0019220 | regulation of phosphate metabolic process | IEP | Predicted GO |
MF | GO:0019899 | enzyme binding | IEP | Predicted GO |
MF | GO:0019900 | kinase binding | IEP | Predicted GO |
MF | GO:0019901 | protein kinase binding | IEP | Predicted GO |
BP | GO:0030198 | extracellular matrix organization | IEP | Predicted GO |
CC | GO:0030312 | external encapsulating structure | IEP | Predicted GO |
CC | GO:0031225 | anchored component of membrane | IEP | Predicted GO |
BP | GO:0031399 | regulation of protein modification process | IEP | Predicted GO |
BP | GO:0032268 | regulation of cellular protein metabolic process | IEP | Predicted GO |
BP | GO:0040007 | growth | IEP | Predicted GO |
BP | GO:0042325 | regulation of phosphorylation | IEP | Predicted GO |
BP | GO:0043062 | extracellular structure organization | IEP | Predicted GO |
BP | GO:0043549 | regulation of kinase activity | IEP | Predicted GO |
BP | GO:0045859 | regulation of protein kinase activity | IEP | Predicted GO |
CC | GO:0048046 | apoplast | IEP | Predicted GO |
BP | GO:0050790 | regulation of catalytic activity | IEP | Predicted GO |
BP | GO:0051174 | regulation of phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0051246 | regulation of protein metabolic process | IEP | Predicted GO |
BP | GO:0051338 | regulation of transferase activity | IEP | Predicted GO |
BP | GO:0051726 | regulation of cell cycle | IEP | Predicted GO |
BP | GO:0065009 | regulation of molecular function | IEP | Predicted GO |
BP | GO:0071900 | regulation of protein serine/threonine kinase activity | IEP | Predicted GO |
BP | GO:1904029 | regulation of cyclin-dependent protein kinase activity | IEP | Predicted GO |
No external refs found! |