MA_10427218g0010

Description : (p51615|maox_vitvi : 843.0) NADP-dependent malic enzyme (EC 1.1.1.40) (NADP-ME) - Vitis vinifera (Grape) & (at2g19900 : 821.0) The malic enzyme (EC 1.1.1.40) encoded by AtNADP-ME1 is expressed in response to developmental and cell-specific signals. The enzyme is active in vitro and appears to function as a homohexamer or homooctamer. It is believed to be a cytosolic protein.; NADP-malic enzyme 1 (NADP-ME1); FUNCTIONS IN: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity, oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor, malic enzyme activity; INVOLVED IN: malate metabolic process, protein homooligomerization; LOCATED IN: cytosol; EXPRESSED IN: embryo, sperm cell, root, stamen, seed; EXPRESSED DURING: 4 anthesis, D bilateral stage; CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NADP-malic enzyme 3 (TAIR:AT5G25880.1); Has 9392 Blast hits to 9373 proteins in 2414 species: Archae - 143; Bacteria - 6244; Metazoa - 609; Fungi - 220; Plants - 469; Viruses - 0; Other Eukaryotes - 1707 (source: NCBI BLink). & (reliability: 1642.0) & (original description: no original description)

Gene families : OG_42_0001077 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001077_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_10427218g0010
Cluster	HCCA clusters: Cluster_108

Target	Alias	Description	ECC score	Gene Family Method
At2g19900	No alias	NADP-dependent malic enzyme 1...	0.02	Orthogroups_2024-Update
At5g11670	No alias	NADP-dependent malic enzyme 2...	0.02	Orthogroups_2024-Update
Cre06.g251400	No alias	NADP-malic enzyme 3	0.01	Orthogroups_2024-Update
LOC_Os01g54030	No alias	NADP-dependent malic enzyme, putative, expressed	0.02	Orthogroups_2024-Update
evm.model.contig_743.1	No alias	(p51615\|maox_vitvi : 495.0) NADP-dependent malic enzyme...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004470	malic enzyme activity	None	Extended
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016615	malate dehydrogenase activity	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0051287	NAD binding	IEA	InterProScan predictions
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003885	D-arabinono-1,4-lactone oxidase activity	IEP	Predicted GO
MF	GO:0003993	acid phosphatase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR012302	Malic_NAD-bd	344	568
IPR012301	Malic_N_dom	117	297

External Links

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MA_10427218g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation