Description : (at5g63910 : 512.0) Encodes a farnesylcysteine lyase (EC 1.8.3.5) involved in a salvage /detoxification pathway of farnesylcysteine (FC) residues that are liberated during the degradation of prenylated proteins. Because FC is a competitive inhibitor of prenylcysteine methyltransferases involved in the down-regulation of ABA signaling, fcly mutants with elevated FC levels are hypersensitive to ABA. The protein also appears to be glycosylated when translated in vitro in the presence of microsomal membranes and it likely requires FAD for enzymatic activity.; farnesylcysteine lyase (FCLY); FUNCTIONS IN: prenylcysteine oxidase activity; INVOLVED IN: prenylated protein catabolic process, abscisic acid mediated signaling pathway, farnesyl diphosphate metabolic process; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Prenylcysteine lyase (InterPro:IPR010795), Prenylcysteine oxidase (InterPro:IPR017046); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1024.0) & (original description: no original description)
Gene families : OG_42_0004385 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004385_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_10435221g0010 | |
Cluster | HCCA clusters: Cluster_90 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Mp5g13980.1 | No alias | Enzyme classification.EC_1 oxidoreductases.EC_1.8... | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor | IEA | InterProScan predictions |
BP | GO:0030328 | prenylcysteine catabolic process | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000375 | RNA splicing, via transesterification reactions | IEP | Predicted GO |
BP | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | IEP | Predicted GO |
BP | GO:0000398 | mRNA splicing, via spliceosome | IEP | Predicted GO |
CC | GO:0005681 | spliceosomal complex | IEP | Predicted GO |
BP | GO:0006397 | mRNA processing | IEP | Predicted GO |
BP | GO:0007034 | vacuolar transport | IEP | Predicted GO |
BP | GO:0008380 | RNA splicing | IEP | Predicted GO |
BP | GO:0016071 | mRNA metabolic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR010795 | Prenylcys_lyase | 155 | 477 |
No external refs found! |