MA_10435887g0040


Description : (q40345|idhp_medsa : 774.0) Isocitrate dehydrogenase [NADP], chloroplast precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (Fragment) - Medicago sativa (Alfalfa) & (at1g65930 : 734.0) Encodes a NADP+-isocitrate dehydrogenase that is believed to function in the cytosol. It appears to contribute to NADPH production under oxidative stress, and thereby to participate in redox signalling linked to defense responses.; cytosolic NADP+-dependent isocitrate dehydrogenase (cICDH); FUNCTIONS IN: isocitrate dehydrogenase (NADP+) activity, copper ion binding; INVOLVED IN: in 7 processes; LOCATED IN: cytosol, apoplast, plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate dehydrogenase NADP-dependent, eukaryotic (InterPro:IPR004790), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: isocitrate dehydrogenase (TAIR:AT1G54340.1); Has 5437 Blast hits to 5413 proteins in 1130 species: Archae - 48; Bacteria - 1243; Metazoa - 817; Fungi - 231; Plants - 475; Viruses - 0; Other Eukaryotes - 2623 (source: NCBI BLink). & (reliability: 1468.0) & (original description: no original description)


Gene families : OG_42_0001789 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001789_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_10435887g0040
Cluster HCCA clusters: Cluster_96

Target Alias Description ECC score Gene Family Method Actions
A4A49_01706 No alias isocitrate dehydrogenase [nadp] 0.03 Orthogroups_2024-Update
evm.model.tig00020610.33 No alias (at1g65930 : 579.0) Encodes a NADP+-isocitrate... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003855 3-dehydroquinate dehydratase activity IEP Predicted GO
MF GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEP Predicted GO
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004356 glutamate-ammonia ligase activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004764 shikimate 3-dehydrogenase (NADP+) activity IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006541 glutamine metabolic process IEP Predicted GO
BP GO:0006542 glutamine biosynthetic process IEP Predicted GO
MF GO:0008171 O-methyltransferase activity IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009057 macromolecule catabolic process IEP Predicted GO
BP GO:0009064 glutamine family amino acid metabolic process IEP Predicted GO
BP GO:0009084 glutamine family amino acid biosynthetic process IEP Predicted GO
BP GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient IEP Predicted GO
BP GO:0015991 ATP hydrolysis coupled proton transport IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
MF GO:0016211 ammonia ligase activity IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016836 hydro-lyase activity IEP Predicted GO
MF GO:0016880 acid-ammonia (or amide) ligase activity IEP Predicted GO
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
CC GO:0019773 proteasome core complex, alpha-subunit complex IEP Predicted GO
MF GO:0019842 vitamin binding IEP Predicted GO
MF GO:0030170 pyridoxal phosphate binding IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
CC GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain IEP Predicted GO
BP GO:0042592 homeostatic process IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
BP GO:0065008 regulation of biological quality IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
MF GO:0070279 vitamin B6 binding IEP Predicted GO
BP GO:0090662 ATP hydrolysis coupled transmembrane transport IEP Predicted GO
BP GO:0099131 ATP hydrolysis coupled ion transmembrane transport IEP Predicted GO
BP GO:0099132 ATP hydrolysis coupled cation transmembrane transport IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR024084 IsoPropMal-DH-like_dom 40 435
No external refs found!