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  5. MA_10436445g0020

MA_10436445g0020


Description : (at1g15750 : 1515.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 3030.0) & (original description: no original description)


Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_10436445g0020
Cluster HCCA clusters: Cluster_201

Target Alias Description ECC score Gene Family Method Actions
At1g15750 No alias Protein TOPLESS [Source:UniProtKB/Swiss-Prot;Acc:Q94AI7] 0.03 Orthogroups_2024-Update
Bradi1g67800 No alias TOPLESS-related 1 0.04 Orthogroups_2024-Update
Glyma.15G006100 No alias TOPLESS-related 1 0.03 Orthogroups_2024-Update
Glyma.20G238400 No alias TOPLESS-related 3 0.03 Orthogroups_2024-Update
HORVU0Hr1G008690.1 No alias transcriptional co-repressor *(TPL/TPR) & auxin... 0.03 Orthogroups_2024-Update
HORVU6Hr1G036010.9 No alias Unknown function 0.02 Orthogroups_2024-Update
Kfl00881_0020 kfl00881_0020_v1.1 (at1g15750 : 1113.0) Encodes a protein with several WD40... 0.02 Orthogroups_2024-Update
Mp7g17410.1 No alias transcriptional repressor (TPL). transcriptional... 0.02 Orthogroups_2024-Update
PSME_00009167-RA No alias (at3g16830 : 184.0) TOPLESS-related 2 (TPR2); FUNCTIONS... 0.01 Orthogroups_2024-Update
PSME_00014296-RA No alias (at1g15750 : 556.0) Encodes a protein with several WD40... 0.05 Orthogroups_2024-Update
Potri.018G128000 No alias WUS-interacting protein 2 0.04 Orthogroups_2024-Update
Pp1s99_260V6 No alias tpl protein binding protein homodimerization... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Predicted GO
BP GO:0000097 sulfur amino acid biosynthetic process IEP Predicted GO
MF GO:0003712 transcription coregulator activity IEP Predicted GO
MF GO:0003714 transcription corepressor activity IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Predicted GO
MF GO:0003997 acyl-CoA oxidase activity IEP Predicted GO
MF GO:0004427 inorganic diphosphatase activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005516 calmodulin binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005777 peroxisome IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006555 methionine metabolic process IEP Predicted GO
BP GO:0006631 fatty acid metabolic process IEP Predicted GO
BP GO:0006635 fatty acid beta-oxidation IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006888 ER to Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
MF GO:0008270 zinc ion binding IEP Predicted GO
BP GO:0009062 fatty acid catabolic process IEP Predicted GO
BP GO:0009066 aspartate family amino acid metabolic process IEP Predicted GO
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Predicted GO
BP GO:0009086 methionine biosynthetic process IEP Predicted GO
MF GO:0009678 hydrogen-translocating pyrophosphatase activity IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015399 primary active transmembrane transporter activity IEP Predicted GO
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity IEP Predicted GO
BP GO:0015672 monovalent inorganic cation transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
CC GO:0016021 integral component of membrane IEP Predicted GO
BP GO:0016042 lipid catabolic process IEP Predicted GO
BP GO:0016054 organic acid catabolic process IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEP Predicted GO
MF GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
BP GO:0019395 fatty acid oxidation IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
MF GO:0022804 active transmembrane transporter activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
BP GO:0030258 lipid modification IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
CC GO:0031224 intrinsic component of membrane IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0034220 ion transmembrane transport IEP Predicted GO
BP GO:0034440 lipid oxidation IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Predicted GO
CC GO:0042579 microbody IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
MF GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
MF GO:0043492 ATPase activity, coupled to movement of substances IEP Predicted GO
BP GO:0044242 cellular lipid catabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046395 carboxylic acid catabolic process IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
MF GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEP Predicted GO
BP GO:0048193 Golgi vesicle transport IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0072329 monocarboxylic acid catabolic process IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
BP GO:0098655 cation transmembrane transport IEP Predicted GO
BP GO:0098660 inorganic ion transmembrane transport IEP Predicted GO
BP GO:0098662 inorganic cation transmembrane transport IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 922 955
IPR001680 WD40_repeat 453 487
No external refs found!