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- MA_10436537g0010
MA_10436537g0010
Description : (at1g10930 : 901.0) DNA helicase involved in the maintenance of genome stability by modulation of the DNA damage response and suppression of homologous recombination.; RECQ4A; FUNCTIONS IN: helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, ATP binding; INVOLVED IN: chromosome organization, response to DNA damage stimulus, double-strand break repair via homologous recombination; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: RECQ helicase L4B (TAIR:AT1G60930.1); Has 34923 Blast hits to 34782 proteins in 2821 species: Archae - 633; Bacteria - 21324; Metazoa - 3687; Fungi - 2728; Plants - 1606; Viruses - 18; Other Eukaryotes - 4927 (source: NCBI BLink). & (reliability: 1802.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Picea release: MA_10436537g0010 | |
Cluster | HCCA clusters: Cluster_58 | |
Expression Context Conservation (ECC)
Target | Alias | Description | ECC score | Gene Family Method | Actions |
Kfl00086_0370 | kfl00086_0370_v1.1 | (at3g05740 : 520.0) RECQ helicase l1 (RECQI1); FUNCTIONS... | 0.01 | Orthogroups_2024-Update | |
evm.model.tig00020961.28 | No alias | (at4g35740 : 303.0) Encodes RECQ3, an ATP-dependent... | 0.01 | Orthogroups_2024-Update | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0000166 | nucleotide binding | None | Extended |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0003676 | nucleic acid binding | IEA | InterProScan predictions |
MF | GO:0003678 | DNA helicase activity | None | Extended |
MF | GO:0003824 | catalytic activity | None | Extended |
MF | GO:0004003 | ATP-dependent DNA helicase activity | None | Extended |
MF | GO:0004386 | helicase activity | None | Extended |
MF | GO:0005488 | binding | None | Extended |
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
BP | GO:0006139 | nucleobase-containing compound metabolic process | None | Extended |
BP | GO:0006259 | DNA metabolic process | None | Extended |
BP | GO:0006260 | DNA replication | IEA | InterProScan predictions |
BP | GO:0006281 | DNA repair | IEA | InterProScan predictions |
BP | GO:0006725 | cellular aromatic compound metabolic process | None | Extended |
BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
BP | GO:0006950 | response to stress | None | Extended |
BP | GO:0006974 | cellular response to DNA damage stimulus | None | Extended |
MF | GO:0008026 | ATP-dependent helicase activity | None | Extended |
MF | GO:0008094 | DNA-dependent ATPase activity | None | Extended |
MF | GO:0008144 | drug binding | None | Extended |
BP | GO:0008150 | biological_process | None | Extended |
BP | GO:0008152 | metabolic process | None | Extended |
BP | GO:0009058 | biosynthetic process | None | Extended |
BP | GO:0009059 | macromolecule biosynthetic process | None | Extended |
BP | GO:0009987 | cellular process | None | Extended |
MF | GO:0016462 | pyrophosphatase activity | None | Extended |
MF | GO:0016787 | hydrolase activity | None | Extended |
MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | None | Extended |
MF | GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | None | Extended |
MF | GO:0016887 | ATPase activity | None | Extended |
MF | GO:0017076 | purine nucleotide binding | None | Extended |
MF | GO:0017111 | nucleoside-triphosphatase activity | None | Extended |
MF | GO:0030554 | adenyl nucleotide binding | None | Extended |
MF | GO:0032553 | ribonucleotide binding | None | Extended |
MF | GO:0032555 | purine ribonucleotide binding | None | Extended |
MF | GO:0032559 | adenyl ribonucleotide binding | None | Extended |
BP | GO:0033554 | cellular response to stress | None | Extended |
BP | GO:0034641 | cellular nitrogen compound metabolic process | None | Extended |
BP | GO:0034645 | cellular macromolecule biosynthetic process | None | Extended |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | None | Extended |
MF | GO:0036094 | small molecule binding | None | Extended |
MF | GO:0042623 | ATPase activity, coupled | None | Extended |
MF | GO:0043138 | 3'-5' DNA helicase activity | None | Extended |
MF | GO:0043140 | ATP-dependent 3'-5' DNA helicase activity | IEA | InterProScan predictions |
MF | GO:0043167 | ion binding | None | Extended |
MF | GO:0043168 | anion binding | None | Extended |
BP | GO:0043170 | macromolecule metabolic process | None | Extended |
BP | GO:0044237 | cellular metabolic process | None | Extended |
BP | GO:0044238 | primary metabolic process | None | Extended |
BP | GO:0044249 | cellular biosynthetic process | None | Extended |
BP | GO:0044260 | cellular macromolecule metabolic process | None | Extended |
BP | GO:0046483 | heterocycle metabolic process | None | Extended |
BP | GO:0050896 | response to stimulus | None | Extended |
BP | GO:0051716 | cellular response to stimulus | None | Extended |
MF | GO:0070035 | purine NTP-dependent helicase activity | None | Extended |
BP | GO:0071704 | organic substance metabolic process | None | Extended |
BP | GO:0090304 | nucleic acid metabolic process | None | Extended |
MF | GO:0097159 | organic cyclic compound binding | None | Extended |
MF | GO:0097367 | carbohydrate derivative binding | None | Extended |
MF | GO:0140097 | catalytic activity, acting on DNA | None | Extended |
MF | GO:1901265 | nucleoside phosphate binding | None | Extended |
BP | GO:1901360 | organic cyclic compound metabolic process | None | Extended |
MF | GO:1901363 | heterocyclic compound binding | None | Extended |
BP | GO:1901576 | organic substance biosynthetic process | None | Extended |
Type | GO Term | Name | Evidence | Source |
MF | GO:0004097 | catechol oxidase activity | IEP | Predicted GO |
MF | GO:0016679 | oxidoreductase activity, acting on diphenols and related substances as donors | IEP | Predicted GO |
MF | GO:0016682 | oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor | IEP | Predicted GO |
CC | GO:0019867 | outer membrane | IEP | Predicted GO |