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  5. MA_112542g0010

MA_112542g0010


Description : (p09342|ilv1_tobac : 916.0) Acetolactate synthase 1, chloroplast precursor (EC 2.2.1.6) (Acetolactate synthase I) (Acetohydroxy-acid synthase I) (ALS I) - Nicotiana tabacum (Common tobacco) & (at3g48560 : 913.0) Catalyzes the formation of acetolactate from pyruvate, the first step in valine and isoleucine biosynthesis. Requires FAD, thiamine pyrophosphate and Mg. Inhibited by the sulphonylurea herbicide, chlorsulphuron, and the imidazolinone herbicide, imazapyr. The obtained crystal structure of acetohydroxyacid synthase AHAS, EC 2.2.1.6)in complex with herbicides of the sulphonylurea and imidazolinone family reveals the molecular basis for substrate/inhibitor binding.; chlorsulfuron/imidazolinone resistant 1 (CSR1); FUNCTIONS IN: acetolactate synthase activity, pyruvate decarboxylase activity; INVOLVED IN: branched chain family amino acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TPP-binding enzyme, conserved site (InterPro:IPR000399), Thiamine pyrophosphate enzyme, central domain (InterPro:IPR012000), Acetolactate synthase, large subunit, biosynthetic (InterPro:IPR012846), Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (InterPro:IPR012001), Thiamine pyrophosphate enzyme, C-terminal TPP-binding (InterPro:IPR011766); BEST Arabidopsis thaliana protein match is: Thiamine pyrophosphate dependent pyruvate decarboxylase family protein (TAIR:AT5G17380.1); Has 30963 Blast hits to 30605 proteins in 2694 species: Archae - 488; Bacteria - 17421; Metazoa - 266; Fungi - 871; Plants - 599; Viruses - 25; Other Eukaryotes - 11293 (source: NCBI BLink). & (reliability: 1826.0) & (original description: no original description)


Gene families : OG_42_0003559 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003559_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_112542g0010
Cluster HCCA clusters: Cluster_146

Target Alias Description ECC score Gene Family Method Actions
Glyma.06G169700 No alias chlorsulfuron/imidazolinone resistant 1 0.03 Orthogroups_2024-Update
evm.model.tig00020516.21 No alias (at3g48560 : 698.0) Catalyzes the formation of... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEA InterProScan predictions
MF GO:0003824 catalytic activity IEA InterProScan predictions
MF GO:0030976 thiamine pyrophosphate binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0005092 GDP-dissociation inhibitor activity IEP Predicted GO
MF GO:0005094 Rho GDP-dissociation inhibitor activity IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005737 cytoplasm IEP Predicted GO
MF GO:0008519 ammonium transmembrane transporter activity IEP Predicted GO
MF GO:0010181 FMN binding IEP Predicted GO
BP GO:0015696 ammonium transport IEP Predicted GO
MF GO:0016854 racemase and epimerase activity IEP Predicted GO
MF GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives IEP Predicted GO
MF GO:0030695 GTPase regulator activity IEP Predicted GO
MF GO:0036361 racemase activity, acting on amino acids and derivatives IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
MF GO:0060589 nucleoside-triphosphatase regulator activity IEP Predicted GO
InterPro domains Description Start Stop
IPR012001 Thiamin_PyroP_enz_TPP-bd_dom 93 257
IPR012000 Thiamin_PyroP_enz_cen_dom 285 417
IPR011766 TPP_enzyme-bd_C 478 633
No external refs found!