Description : (at3g62980 : 510.0) Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation.; TRANSPORT INHIBITOR RESPONSE 1 (TIR1); CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), F-box domain, Skp2-like (InterPro:IPR022364); BEST Arabidopsis thaliana protein match is: GRR1-like protein 1 (TAIR:AT4G03190.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1020.0) & (original description: no original description)
Gene families : OG_42_0000339 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000339_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_15842g0010 | |
Cluster | HCCA clusters: Cluster_191 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
At3g26810 | No alias | AFB2 [Source:UniProtKB/TrEMBL;Acc:A0A178VGF7] | 0.03 | Orthogroups_2024-Update | |
Bradi1g67160 | No alias | RNI-like superfamily protein | 0.03 | Orthogroups_2024-Update | |
Glyma.14G179500 | No alias | auxin F-box protein 5 | 0.02 | Orthogroups_2024-Update | |
LOC_Os03g15880 | No alias | coronatine-insensitive protein, putative, expressed | 0.02 | Orthogroups_2024-Update | |
Pp1s196_87V6 | No alias | f-box family protein | 0.03 | Orthogroups_2024-Update | |
Pp1s49_196V6 | No alias | TLP3A TIR1-like auxin receptor protein | 0.02 | Orthogroups_2024-Update | |
Sobic.006G056000.1 | No alias | substrate adaptor of SCF E3 ubiquitin ligase *(TIR1/AFB) | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
MF | GO:0005319 | lipid transporter activity | IEP | Predicted GO |
CC | GO:0005737 | cytoplasm | IEP | Predicted GO |
BP | GO:0006511 | ubiquitin-dependent protein catabolic process | IEP | Predicted GO |
BP | GO:0006869 | lipid transport | IEP | Predicted GO |
BP | GO:0007275 | multicellular organism development | IEP | Predicted GO |
MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
BP | GO:0019941 | modification-dependent protein catabolic process | IEP | Predicted GO |
BP | GO:0032501 | multicellular organismal process | IEP | Predicted GO |
BP | GO:0032502 | developmental process | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
MF | GO:0043168 | anion binding | IEP | Predicted GO |
BP | GO:0043632 | modification-dependent macromolecule catabolic process | IEP | Predicted GO |
BP | GO:0044265 | cellular macromolecule catabolic process | IEP | Predicted GO |
BP | GO:0048856 | anatomical structure development | IEP | Predicted GO |
BP | GO:0051603 | proteolysis involved in cellular protein catabolic process | IEP | Predicted GO |
BP | GO:0061024 | membrane organization | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
BP | GO:0120009 | intermembrane lipid transfer | IEP | Predicted GO |
MF | GO:0120013 | intermembrane lipid transfer activity | IEP | Predicted GO |
MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001611 | Leu-rich_rpt | 84 | 101 |
No external refs found! |