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  5. MA_169054g0020

MA_169054g0020


Description : (p50567|h2a_chlre : 140.0) Histone H2A - Chlamydomonas reinhardtii & (at1g08880 : 133.0) Encodes HTA5, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; H2AXA; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: gamma histone variant H2AX (TAIR:AT1G54690.1); Has 3916 Blast hits to 3911 proteins in 363 species: Archae - 0; Bacteria - 0; Metazoa - 2550; Fungi - 318; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 266.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_169054g0020
Cluster HCCA clusters: Cluster_22

Target Alias Description ECC score Gene Family Method Actions
A4A49_56752 No alias putative histone h2a.1 0.03 Orthogroups_2024-Update
Bradi2g23090 No alias histone H2A 12 0.04 Orthogroups_2024-Update
GRMZM2G041381 No alias histone H2A 2 0.03 Orthogroups_2024-Update
GRMZM2G151726 No alias histone H2A 2 0.04 Orthogroups_2024-Update
HORVU5Hr1G105090.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
HORVU7Hr1G030120.1 No alias histone *(H2A) 0.04 Orthogroups_2024-Update
LOC_Os03g17100 No alias Core histone H2A/H2B/H3/H4 domain containing protein,... 0.02 Orthogroups_2024-Update
LOC_Os12g25120 No alias core histone H2A/H2B/H3/H4, putative, expressed 0.02 Orthogroups_2024-Update
PSME_00017670-RA No alias (p35063|h2ax_picab : 188.0) Histone H2AX - Picea abies... 0.04 Orthogroups_2024-Update
Sobic.009G015900.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0006631 fatty acid metabolic process IEP Predicted GO
BP GO:0006633 fatty acid biosynthetic process IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR032454 Histone_H2A_C 99 131
IPR007125 Histone_H2A/H2B/H3 18 96
No external refs found!