Description : (at1g15750 : 344.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 688.0) & (original description: no original description)
Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_16979g0020 | |
Cluster | HCCA clusters: Cluster_170 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_33343 | No alias | protein topless | 0.02 | Orthogroups_2024-Update | |
Bradi1g67800 | No alias | TOPLESS-related 1 | 0.02 | Orthogroups_2024-Update | |
Glyma.03G233400 | No alias | TOPLESS-related 3 | 0.03 | Orthogroups_2024-Update | |
Glyma.13G367300 | No alias | TOPLESS-related 1 | 0.03 | Orthogroups_2024-Update | |
Glyma.15G006100 | No alias | TOPLESS-related 1 | 0.05 | Orthogroups_2024-Update | |
LOC_Os01g15020 | No alias | lissencephaly type-1-like homology motif, putative, expressed | 0.02 | Orthogroups_2024-Update | |
Mp7g17410.1 | No alias | transcriptional repressor (TPL). transcriptional... | 0.03 | Orthogroups_2024-Update | |
PSME_00001044-RA | No alias | (at1g15750 : 1653.0) Encodes a protein with several WD40... | 0.03 | Orthogroups_2024-Update | |
PSME_00014296-RA | No alias | (at1g15750 : 556.0) Encodes a protein with several WD40... | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
MF | GO:0003682 | chromatin binding | IEP | Predicted GO |
MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
MF | GO:0004674 | protein serine/threonine kinase activity | IEP | Predicted GO |
MF | GO:0005524 | ATP binding | IEP | Predicted GO |
CC | GO:0005634 | nucleus | IEP | Predicted GO |
BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
MF | GO:0008144 | drug binding | IEP | Predicted GO |
MF | GO:0015298 | solute:cation antiporter activity | IEP | Predicted GO |
MF | GO:0015299 | solute:proton antiporter activity | IEP | Predicted GO |
MF | GO:0016301 | kinase activity | IEP | Predicted GO |
MF | GO:0016307 | phosphatidylinositol phosphate kinase activity | IEP | Predicted GO |
BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEP | Predicted GO |
MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
MF | GO:0022804 | active transmembrane transporter activity | IEP | Predicted GO |
CC | GO:0030117 | membrane coat | IEP | Predicted GO |
CC | GO:0030120 | vesicle coat | IEP | Predicted GO |
CC | GO:0030126 | COPI vesicle coat | IEP | Predicted GO |
MF | GO:0030554 | adenyl nucleotide binding | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032559 | adenyl ribonucleotide binding | IEP | Predicted GO |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
MF | GO:0043167 | ion binding | IEP | Predicted GO |
MF | GO:0043168 | anion binding | IEP | Predicted GO |
CC | GO:0043227 | membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0043231 | intracellular membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0044431 | Golgi apparatus part | IEP | Predicted GO |
CC | GO:0044433 | cytoplasmic vesicle part | IEP | Predicted GO |
BP | GO:0046488 | phosphatidylinositol metabolic process | IEP | Predicted GO |
BP | GO:0051726 | regulation of cell cycle | IEP | Predicted GO |
MF | GO:0097159 | organic cyclic compound binding | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
MF | GO:1901363 | heterocyclic compound binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001680 | WD40_repeat | 63 | 96 |
No external refs found! |