MA_16979g0020


Description : (at1g15750 : 344.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 688.0) & (original description: no original description)


Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_16979g0020
Cluster HCCA clusters: Cluster_170

Target Alias Description ECC score Gene Family Method Actions
A4A49_33343 No alias protein topless 0.02 Orthogroups_2024-Update
Bradi1g67800 No alias TOPLESS-related 1 0.02 Orthogroups_2024-Update
Glyma.03G233400 No alias TOPLESS-related 3 0.03 Orthogroups_2024-Update
Glyma.13G367300 No alias TOPLESS-related 1 0.03 Orthogroups_2024-Update
Glyma.15G006100 No alias TOPLESS-related 1 0.05 Orthogroups_2024-Update
LOC_Os01g15020 No alias lissencephaly type-1-like homology motif, putative, expressed 0.02 Orthogroups_2024-Update
Mp7g17410.1 No alias transcriptional repressor (TPL). transcriptional... 0.03 Orthogroups_2024-Update
PSME_00001044-RA No alias (at1g15750 : 1653.0) Encodes a protein with several WD40... 0.03 Orthogroups_2024-Update
PSME_00014296-RA No alias (at1g15750 : 556.0) Encodes a protein with several WD40... 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003682 chromatin binding IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0004674 protein serine/threonine kinase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0015298 solute:cation antiporter activity IEP Predicted GO
MF GO:0015299 solute:proton antiporter activity IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
MF GO:0016307 phosphatidylinositol phosphate kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0022804 active transmembrane transporter activity IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
BP GO:0046488 phosphatidylinositol metabolic process IEP Predicted GO
BP GO:0051726 regulation of cell cycle IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 63 96
No external refs found!