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  5. MA_187851g0010

MA_187851g0010


Description : (at4g21070 : 105.0) Encodes AtBRCA1, an ortholog of the human breast cancer susceptibility gene 1. Contains one N-terminal RING finger, two C-terminal BRCT and the p300/CBP interacting domain. Strongly induced by gamma rays, consistent with a putative role in DNA repair and in cell cycle control.; breast cancer susceptibility1 (BRCA1); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: DNA repair, response to gamma radiation; LOCATED IN: intracellular, nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), BRCA1 (InterPro:IPR011364), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: breast cancer associated RING 1 (TAIR:AT1G04020.2); Has 8999 Blast hits to 8407 proteins in 1134 species: Archae - 0; Bacteria - 191; Metazoa - 6557; Fungi - 520; Plants - 721; Viruses - 32; Other Eukaryotes - 978 (source: NCBI BLink). & (reliability: 210.0) & (original description: no original description)


Gene families : OG_42_0000927 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000927_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_187851g0010
Cluster HCCA clusters: Cluster_190

Target Alias Description ECC score Gene Family Method Actions
Brara.H01075.1 No alias component *(BRCA1/BARD1) of BRCA1-BARD1 ubiquitination... 0.03 Orthogroups_2024-Update
Cre07.g334650 No alias breast cancer susceptibility1 0.02 Orthogroups_2024-Update
Glyma.13G220400 No alias breast cancer susceptibility1 0.03 Orthogroups_2024-Update
Kfl00116_0090 kfl00116_0090_v1.... (at1g04020 : 184.0) Encodes a protein containing two... 0.01 Orthogroups_2024-Update
PSME_00038950-RA No alias (at1g04020 : 236.0) Encodes a protein containing two... 0.03 Orthogroups_2024-Update
PSME_00040905-RA No alias (at1g04020 : 158.0) Encodes a protein containing two... 0.03 Orthogroups_2024-Update
Sobic.006G144700.1 No alias component *(BRCA1/BARD1) of BRCA1-BARD1 ubiquitination... 0.03 Orthogroups_2024-Update
Solyc06g008210 No alias breast cancer associated RING 1 (AHRD V3.3 *** AT1G04020.1) 0.03 Orthogroups_2024-Update
Sopen06g003070 No alias BRCA1 C Terminus (BRCT) domain 0.03 Orthogroups_2024-Update
evm.model.tig00020537.14 No alias (at1g04020 : 90.1) Encodes a protein containing two... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003774 motor activity IEP Predicted GO
MF GO:0003777 microtubule motor activity IEP Predicted GO
MF GO:0003896 DNA primase activity IEP Predicted GO
MF GO:0003916 DNA topoisomerase activity IEP Predicted GO
MF GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity IEP Predicted GO
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006265 DNA topological change IEP Predicted GO
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Predicted GO
BP GO:0006270 DNA replication initiation IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006928 movement of cell or subcellular component IEP Predicted GO
BP GO:0007017 microtubule-based process IEP Predicted GO
BP GO:0007018 microtubule-based movement IEP Predicted GO
MF GO:0008017 microtubule binding IEP Predicted GO
MF GO:0008092 cytoskeletal protein binding IEP Predicted GO
MF GO:0008094 DNA-dependent ATPase activity IEP Predicted GO
MF GO:0015631 tubulin binding IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0051052 regulation of DNA metabolic process IEP Predicted GO
BP GO:0051276 chromosome organization IEP Predicted GO
MF GO:0061505 DNA topoisomerase II activity IEP Predicted GO
BP GO:0071103 DNA conformation change IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!