MA_19532g0010

Description : (at3g16770 : 106.0) Encodes a member of the ERF (ethylene response factor) subfamily B-2 of the plant specific ERF/AP2 transcription factor family (RAP2.3). The protein contains one AP2 domain. There are 5 members in this subfamily including RAP2.2 AND RAP2.12.It is localized to the nucleus and acts as a transcriptional activator through the GCC-box. It has been identified as a suppressor of Bax-induced cell death by functional screening in yeast and can also suppress Bax-induced cell death in tobacco plants. Overexpression of this gene in tobacco BY-2 cells confers resistance to H2O2 and heat stresses. Overexpression in Arabidopsis causes upregulation of PDF1.2 and GST6. It is part of the ethylene signaling pathway and is predicted to act downstream of EIN2 and CTR1, but not under EIN3.; ethylene-responsive element binding protein (EBP); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT2G47520.1); Has 5957 Blast hits to 5752 proteins in 250 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 5929; Viruses - 4; Other Eukaryotes - 24 (source: NCBI BLink). & (q6k7e6|erf1_orysa : 94.7) Ethylene-responsive transcription factor 1 (Ethylene-responsive element-binding factor 1) (EREBP-1) (OsEREBP1) - Oryza sativa (Rice) & (reliability: 212.0) & (original description: no original description)

Gene families : OG_42_0000000 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_19532g0010
Cluster	HCCA clusters: Cluster_61

Target	Alias	Description	ECC score	Gene Family Method
A4A49_27754	No alias	ethylene-responsive transcription factor 1a	0.03	Orthogroups_2024-Update
Bradi1g75040	No alias	Integrase-type DNA-binding superfamily protein	0.02	Orthogroups_2024-Update
LOC_Os04g44670	No alias	AP2 domain containing protein, expressed	0.02	Orthogroups_2024-Update
PSME_00000850-RA	No alias	no hits & (original description: no original description)	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003700	DNA-binding transcription factor activity	IEA	InterProScan predictions
BP	GO:0006355	regulation of transcription, DNA-templated	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0140110	transcription regulator activity	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003690	double-stranded DNA binding	IEP	Predicted GO
MF	GO:0005507	copper ion binding	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006298	mismatch repair	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001471	AP2/ERF_dom	98	146

External Links

No external refs found!

MA_19532g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation