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MA_2215g0010


Description : (at3g01120 : 111.0) encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.; METHIONINE OVERACCUMULATION 1 (MTO1); FUNCTIONS IN: cystathionine gamma-synthase activity; INVOLVED IN: methionine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT1G33320.1); Has 21364 Blast hits to 20702 proteins in 2452 species: Archae - 220; Bacteria - 11705; Metazoa - 241; Fungi - 842; Plants - 284; Viruses - 13; Other Eukaryotes - 8059 (source: NCBI BLink). & (reliability: 222.0) & (original description: no original description)


Gene families : OG_42_0016379 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0016379_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_2215g0010
Cluster HCCA clusters: Cluster_251


Type GO Term Name Evidence Source
MF GO:0030170 pyridoxal phosphate binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
InterPro domains Description Start Stop
IPR000277 Cys/Met-Metab_PyrdxlP-dep_enz 26 188
IPR000277 Cys/Met-Metab_PyrdxlP-dep_enz 203 361
No external refs found!