Description : (at5g13960 : 265.0) Encodes a histone 3 lysine 9 specific methyltransferase involved in the maintenance of DNA methylation. SUVH4/KYP is a SU(VAR)3-9 homolog, a SET domain protein. Known SET domain proteins are involved in epigenetic control of gene expression. There are 10 SUVH genes in Arabidopsis and members of this subfamily of the SET proteins have an additional conserved SRA domain. In kyp mutants, there is a loss of CpNpG methylation. The protein was shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the latter two. There is also evidence that KYP/SUVH4 might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres.; SU(VAR)3-9 homolog 4 (SUVH4); FUNCTIONS IN: double-stranded methylated DNA binding, methyl-CpNpG binding, methyl-CpG binding, histone methyltransferase activity (H3-K9 specific), methyl-CpNpN binding; INVOLVED IN: maintenance of DNA methylation, histone methylation, peptidyl-lysine methylation, histone H3-K9 methylation; LOCATED IN: nucleus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), SRA-YDG (InterPro:IPR003105), Pre-SET domain (InterPro:IPR007728), Post-SET domain (InterPro:IPR003616); BEST Arabidopsis thaliana protein match is: SU(VAR)3-9 homolog 6 (TAIR:AT2G22740.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 530.0) & (original description: no original description)
Gene families : OG_42_0000288 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000288_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_22288g0010 | |
Cluster | HCCA clusters: Cluster_102 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Bradi1g29010 | No alias | SU(VAR)3-9 homolog 2 | 0.04 | Orthogroups_2024-Update | |
Bradi2g60080 | No alias | SU(VAR)3-9 homolog 9 | 0.04 | Orthogroups_2024-Update | |
Brara.E00919.1 | No alias | histone H3K9 methyltransferase *(SUVH5/6) & EC_2.1... | 0.04 | Orthogroups_2024-Update | |
GRMZM2G140577 | No alias | SU(VAR)3-9 homolog 3 | 0.03 | Orthogroups_2024-Update | |
Glyma.20G069300 | No alias | SU(VAR)3-9 homolog 5 | 0.03 | Orthogroups_2024-Update | |
Mp3g05860.1 | No alias | class V/Su(var) histone methyltransferase component of... | 0.02 | Orthogroups_2024-Update | |
Sobic.006G165800.1 | No alias | histone H3K9 methyltransferase *(SUVH5/6) & EC_2.1... | 0.02 | Orthogroups_2024-Update | |
Solyc02g094520 | No alias | Histone-lysine N-methyltransferase, H3 lysine-9 specific... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity | IEP | Predicted GO |
MF | GO:0004721 | phosphoprotein phosphatase activity | IEP | Predicted GO |
MF | GO:0005085 | guanyl-nucleotide exchange factor activity | IEP | Predicted GO |
MF | GO:0005088 | Ras guanyl-nucleotide exchange factor activity | IEP | Predicted GO |
MF | GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEP | Predicted GO |
BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
MF | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | IEP | Predicted GO |
BP | GO:0016311 | dephosphorylation | IEP | Predicted GO |
MF | GO:0016410 | N-acyltransferase activity | IEP | Predicted GO |
MF | GO:0016788 | hydrolase activity, acting on ester bonds | IEP | Predicted GO |
MF | GO:0016791 | phosphatase activity | IEP | Predicted GO |
MF | GO:0017016 | Ras GTPase binding | IEP | Predicted GO |
MF | GO:0017048 | Rho GTPase binding | IEP | Predicted GO |
MF | GO:0019107 | myristoyltransferase activity | IEP | Predicted GO |
MF | GO:0019899 | enzyme binding | IEP | Predicted GO |
MF | GO:0031267 | small GTPase binding | IEP | Predicted GO |
MF | GO:0042393 | histone binding | IEP | Predicted GO |
MF | GO:0051020 | GTPase binding | IEP | Predicted GO |
MF | GO:0098772 | molecular function regulator | IEP | Predicted GO |
MF | GO:0140096 | catalytic activity, acting on a protein | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001214 | SET_dom | 82 | 200 |
No external refs found! |