MA_22288g0010


Description : (at5g13960 : 265.0) Encodes a histone 3 lysine 9 specific methyltransferase involved in the maintenance of DNA methylation. SUVH4/KYP is a SU(VAR)3-9 homolog, a SET domain protein. Known SET domain proteins are involved in epigenetic control of gene expression. There are 10 SUVH genes in Arabidopsis and members of this subfamily of the SET proteins have an additional conserved SRA domain. In kyp mutants, there is a loss of CpNpG methylation. The protein was shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the latter two. There is also evidence that KYP/SUVH4 might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres.; SU(VAR)3-9 homolog 4 (SUVH4); FUNCTIONS IN: double-stranded methylated DNA binding, methyl-CpNpG binding, methyl-CpG binding, histone methyltransferase activity (H3-K9 specific), methyl-CpNpN binding; INVOLVED IN: maintenance of DNA methylation, histone methylation, peptidyl-lysine methylation, histone H3-K9 methylation; LOCATED IN: nucleus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), SRA-YDG (InterPro:IPR003105), Pre-SET domain (InterPro:IPR007728), Post-SET domain (InterPro:IPR003616); BEST Arabidopsis thaliana protein match is: SU(VAR)3-9 homolog 6 (TAIR:AT2G22740.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 530.0) & (original description: no original description)


Gene families : OG_42_0000288 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000288_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_22288g0010
Cluster HCCA clusters: Cluster_102

Target Alias Description ECC score Gene Family Method Actions
Bradi1g29010 No alias SU(VAR)3-9 homolog 2 0.04 Orthogroups_2024-Update
Bradi2g60080 No alias SU(VAR)3-9 homolog 9 0.04 Orthogroups_2024-Update
Brara.E00919.1 No alias histone H3K9 methyltransferase *(SUVH5/6) & EC_2.1... 0.04 Orthogroups_2024-Update
GRMZM2G140577 No alias SU(VAR)3-9 homolog 3 0.03 Orthogroups_2024-Update
Glyma.20G069300 No alias SU(VAR)3-9 homolog 5 0.03 Orthogroups_2024-Update
Mp3g05860.1 No alias class V/Su(var) histone methyltransferase component of... 0.02 Orthogroups_2024-Update
Sobic.006G165800.1 No alias histone H3K9 methyltransferase *(SUVH5/6) & EC_2.1... 0.02 Orthogroups_2024-Update
Solyc02g094520 No alias Histone-lysine N-methyltransferase, H3 lysine-9 specific... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004379 glycylpeptide N-tetradecanoyltransferase activity IEP Predicted GO
MF GO:0004721 phosphoprotein phosphatase activity IEP Predicted GO
MF GO:0005085 guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005088 Ras guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005089 Rho guanyl-nucleotide exchange factor activity IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
MF GO:0008138 protein tyrosine/serine/threonine phosphatase activity IEP Predicted GO
BP GO:0016311 dephosphorylation IEP Predicted GO
MF GO:0016410 N-acyltransferase activity IEP Predicted GO
MF GO:0016788 hydrolase activity, acting on ester bonds IEP Predicted GO
MF GO:0016791 phosphatase activity IEP Predicted GO
MF GO:0017016 Ras GTPase binding IEP Predicted GO
MF GO:0017048 Rho GTPase binding IEP Predicted GO
MF GO:0019107 myristoyltransferase activity IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
MF GO:0031267 small GTPase binding IEP Predicted GO
MF GO:0042393 histone binding IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
InterPro domains Description Start Stop
IPR001214 SET_dom 82 200
No external refs found!