MA_22632g0010

Description : (p51615|maox_vitvi : 870.0) NADP-dependent malic enzyme (EC 1.1.1.40) (NADP-ME) - Vitis vinifera (Grape) & (at1g79750 : 843.0) The malic enzyme (EC 1.1.1.40) encoded by AtNADP-ME4 is localized to chloroplasts. The gene is expressed throughout the whole plant and during embryogenesis and germination. A possible involvement in the fatty acid biosynthesis has been proposed.; NADP-malic enzyme 4 (NADP-ME4); CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NADP-malic enzyme 3 (TAIR:AT5G25880.1); Has 9573 Blast hits to 9553 proteins in 2441 species: Archae - 143; Bacteria - 6332; Metazoa - 610; Fungi - 220; Plants - 473; Viruses - 0; Other Eukaryotes - 1795 (source: NCBI BLink). & (reliability: 1686.0) & (original description: no original description)

Gene families : OG_42_0001077 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001077_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_22632g0010
Cluster	HCCA clusters: Cluster_108

Target	Alias	Description	ECC score	Gene Family Method	Actions
Sopen05g028500	No alias	Malic enzyme, NAD binding domain	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004470	malic enzyme activity	None	Extended
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016615	malate dehydrogenase activity	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0051287	NAD binding	IEA	InterProScan predictions
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0003777	microtubule motor activity	IEP	Predicted GO
MF	GO:0003993	acid phosphatase activity	IEP	Predicted GO
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEP	Predicted GO
BP	GO:0006928	movement of cell or subcellular component	IEP	Predicted GO
BP	GO:0007017	microtubule-based process	IEP	Predicted GO
BP	GO:0007018	microtubule-based movement	IEP	Predicted GO
MF	GO:0008017	microtubule binding	IEP	Predicted GO
MF	GO:0015631	tubulin binding	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Predicted GO
MF	GO:0016791	phosphatase activity	IEP	Predicted GO
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR012301	Malic_N_dom	117	297
IPR012302	Malic_NAD-bd	307	558

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MA_22632g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation