Description : (q69f95|c85a_phavu : 572.0) Cytochrome P450 85A (EC 1.14.-.-) (C6-oxidase) - Phaseolus vulgaris (Kidney bean) (French bean) & (at3g30180 : 538.0) Encodes a cytochrome p450 enzyme that catalyzes the last reaction in the production of brassinolide. It is capable of converting 6-deoxocastasterone into castasterone, a C-6 oxidation, as well as the further conversion of castasterone into brassinolide by a Baeyer-Villinger oxidation reaction at C-6, resulting in the formation of an unusual seven-membered lactone ring. The enzyme possesses high affinity for both C28- and C27-Brassinosteroids. The expression of the gene using a CYP85A2 promoter:LUC fusion construct was shown to be under circadian and light control.; brassinosteroid-6-oxidase 2 (BR6OX2); FUNCTIONS IN: monooxygenase activity, oxygen binding; INVOLVED IN: response to light stimulus, circadian rhythm, brassinosteroid biosynthetic process; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: brassinosteroid-6-oxidase 1 (TAIR:AT5G38970.1); Has 29372 Blast hits to 29308 proteins in 1622 species: Archae - 48; Bacteria - 4489; Metazoa - 10449; Fungi - 5456; Plants - 7735; Viruses - 3; Other Eukaryotes - 1192 (source: NCBI BLink). & (reliability: 1076.0) & (original description: no original description)
Gene families : OG_42_0000020 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000020_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_31668g0010 | |
Cluster | HCCA clusters: Cluster_231 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
HORVU5Hr1G043140.1 | No alias | steroid 3-dehydrogenase *(CPD) & EC_1.14 oxidoreductase... | 0.02 | Orthogroups_2024-Update | |
MA_607123g0010 | No alias | (q94iw5|c90d2_orysa : 121.0) Cytochrome P450 90D2 (EC... | 0.04 | Orthogroups_2024-Update | |
Sobic.001G445900.1 | No alias | steroid 22-alpha-hydroxylase *(DWF4) & EC_1.14... | 0.03 | Orthogroups_2024-Update | |
Sopen02g030050 | No alias | Cytochrome P450 | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005506 | iron ion binding | IEA | InterProScan predictions |
MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | InterProScan predictions |
MF | GO:0020037 | heme binding | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004386 | helicase activity | IEP | Predicted GO |
MF | GO:0004556 | alpha-amylase activity | IEP | Predicted GO |
BP | GO:0006281 | DNA repair | IEP | Predicted GO |
BP | GO:0006298 | mismatch repair | IEP | Predicted GO |
BP | GO:0006974 | cellular response to DNA damage stimulus | IEP | Predicted GO |
BP | GO:0008272 | sulfate transport | IEP | Predicted GO |
MF | GO:0008509 | anion transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0008641 | ubiquitin-like modifier activating enzyme activity | IEP | Predicted GO |
MF | GO:0015103 | inorganic anion transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015116 | sulfate transmembrane transporter activity | IEP | Predicted GO |
BP | GO:0015698 | inorganic anion transport | IEP | Predicted GO |
MF | GO:0016160 | amylase activity | IEP | Predicted GO |
MF | GO:0016877 | ligase activity, forming carbon-sulfur bonds | IEP | Predicted GO |
MF | GO:0030983 | mismatched DNA binding | IEP | Predicted GO |
BP | GO:0033554 | cellular response to stress | IEP | Predicted GO |
BP | GO:0051716 | cellular response to stimulus | IEP | Predicted GO |
BP | GO:0072348 | sulfur compound transport | IEP | Predicted GO |
MF | GO:1901682 | sulfur compound transmembrane transporter activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001128 | Cyt_P450 | 34 | 453 |
No external refs found! |