MA_41124g0010


Description : (at4g02070 : 101.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.; MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1). & (reliability: 202.0) & (original description: no original description)


Gene families : OG_42_0001047 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001047_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_41124g0010
Cluster HCCA clusters: Cluster_108

Target Alias Description ECC score Gene Family Method Actions
Seita.2G201300.1 No alias component *(MSH6) of MSH2-x mismatch repair heterodimers 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
CC GO:0000428 DNA-directed RNA polymerase complex IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEP Predicted GO
MF GO:0004427 inorganic diphosphatase activity IEP Predicted GO
MF GO:0004455 ketol-acid reductoisomerase activity IEP Predicted GO
MF GO:0004576 oligosaccharyl transferase activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005665 RNA polymerase II, core complex IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
BP GO:0006366 transcription by RNA polymerase II IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006479 protein methylation IEP Predicted GO
BP GO:0006606 protein import into nucleus IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006888 ER to Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008170 N-methyltransferase activity IEP Predicted GO
BP GO:0008213 protein alkylation IEP Predicted GO
MF GO:0008276 protein methyltransferase activity IEP Predicted GO
MF GO:0008536 Ran GTPase binding IEP Predicted GO
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Predicted GO
BP GO:0009081 branched-chain amino acid metabolic process IEP Predicted GO
BP GO:0009082 branched-chain amino acid biosynthetic process IEP Predicted GO
MF GO:0009678 hydrogen-translocating pyrophosphatase activity IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016278 lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016279 protein-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0016569 covalent chromatin modification IEP Predicted GO
BP GO:0016570 histone modification IEP Predicted GO
BP GO:0016571 histone methylation IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0017016 Ras GTPase binding IEP Predicted GO
BP GO:0017038 protein import IEP Predicted GO
MF GO:0017056 structural constituent of nuclear pore IEP Predicted GO
BP GO:0018022 peptidyl-lysine methylation IEP Predicted GO
MF GO:0018024 histone-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0018205 peptidyl-lysine modification IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
CC GO:0030880 RNA polymerase complex IEP Predicted GO
MF GO:0031267 small GTPase binding IEP Predicted GO
MF GO:0031369 translation initiation factor binding IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0033365 protein localization to organelle IEP Predicted GO
BP GO:0034504 protein localization to nucleus IEP Predicted GO
BP GO:0034613 cellular protein localization IEP Predicted GO
BP GO:0034968 histone lysine methylation IEP Predicted GO
MF GO:0042054 histone methyltransferase activity IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0043414 macromolecule methylation IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0048193 Golgi vesicle transport IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051170 import into nucleus IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
CC GO:0055029 nuclear DNA-directed RNA polymerase complex IEP Predicted GO
MF GO:0061608 nuclear import signal receptor activity IEP Predicted GO
CC GO:0061695 transferase complex, transferring phosphorus-containing groups IEP Predicted GO
BP GO:0070727 cellular macromolecule localization IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0072594 establishment of protein localization to organelle IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
MF GO:0140104 molecular carrier activity IEP Predicted GO
MF GO:0140142 nucleocytoplasmic carrier activity IEP Predicted GO
InterPro domains Description Start Stop
IPR019023 Lamin-B_rcpt_of_tudor 127 167
No external refs found!