MA_42083g0010

Description : (at5g02820 : 650.0) Involved in the patterning and shape of leaf trichomes. Encodes the DNA topoisomerase VI SPO11-3, involved in endoreduplication; ROOT HAIRLESS 2 (RHL2); CONTAINS InterPro DOMAIN/s: Spo11/DNA topoisomerase VI, subunit A, N-terminal (InterPro:IPR013049), DNA topoisomerase VI, subunit A (InterPro:IPR004085), Spo11/DNA topoisomerase VI, subunit A (InterPro:IPR002815); BEST Arabidopsis thaliana protein match is: Spo11/DNA topoisomerase VI, subunit A protein (TAIR:AT3G13170.1); Has 936 Blast hits to 932 proteins in 314 species: Archae - 223; Bacteria - 16; Metazoa - 170; Fungi - 119; Plants - 152; Viruses - 0; Other Eukaryotes - 256 (source: NCBI BLink). & (reliability: 1300.0) & (original description: no original description)

Gene families : OG_42_0001606 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001606_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_42083g0010
Cluster	HCCA clusters: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method	Actions
A4A49_39025	No alias	dna topoisomerase 6 subunit a	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEP	Predicted GO
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Predicted GO
MF	GO:0004664	prephenate dehydratase activity	IEP	Predicted GO
MF	GO:0004860	protein kinase inhibitor activity	IEP	Predicted GO
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006558	L-phenylalanine metabolic process	IEP	Predicted GO
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006787	porphyrin-containing compound catabolic process	IEP	Predicted GO
BP	GO:0007050	cell cycle arrest	IEP	Predicted GO
BP	GO:0009094	L-phenylalanine biosynthetic process	IEP	Predicted GO
CC	GO:0009654	photosystem II oxygen evolving complex	IEP	Predicted GO
BP	GO:0010109	regulation of photosynthesis	IEP	Predicted GO
BP	GO:0010207	photosystem II assembly	IEP	Predicted GO
MF	GO:0010242	oxygen evolving activity	IEP	Predicted GO
BP	GO:0015994	chlorophyll metabolic process	IEP	Predicted GO
BP	GO:0015996	chlorophyll catabolic process	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016859	cis-trans isomerase activity	IEP	Predicted GO
BP	GO:0017003	protein-heme linkage	IEP	Predicted GO
BP	GO:0017004	cytochrome complex assembly	IEP	Predicted GO
BP	GO:0017006	protein-tetrapyrrole linkage	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018208	peptidyl-proline modification	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
MF	GO:0019210	kinase inhibitor activity	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
BP	GO:0022402	cell cycle process	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
MF	GO:0030291	protein serine/threonine kinase inhibitor activity	IEP	Predicted GO
MF	GO:0030410	nicotianamine synthase activity	IEP	Predicted GO
BP	GO:0030417	nicotianamine metabolic process	IEP	Predicted GO
BP	GO:0030418	nicotianamine biosynthetic process	IEP	Predicted GO
BP	GO:0033015	tetrapyrrole catabolic process	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0042440	pigment metabolic process	IEP	Predicted GO
BP	GO:0042548	regulation of photosynthesis, light reaction	IEP	Predicted GO
BP	GO:0042549	photosystem II stabilization	IEP	Predicted GO
BP	GO:0043467	regulation of generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
BP	GO:0045786	negative regulation of cell cycle	IEP	Predicted GO
BP	GO:0046149	pigment catabolic process	IEP	Predicted GO
MF	GO:0047746	chlorophyllase activity	IEP	Predicted GO
BP	GO:0048523	negative regulation of cellular process	IEP	Predicted GO
BP	GO:0051187	cofactor catabolic process	IEP	Predicted GO
BP	GO:0051259	protein complex oligomerization	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Predicted GO
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0072351	tricarboxylic acid biosynthetic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	IEP	Predicted GO
BP	GO:1902223	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013049	Spo11/TopoVI_A_N	142	203

External Links

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MA_42083g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation