MA_4726g0010


Description : (q6f4f5|c724b_orysa : 533.0) Cytochrome P450 724B1 (EC 1.14.-.-) (OsDWARF11) (Dwarf protein 11) - Oryza sativa (Rice) & (at3g50660 : 440.0) Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.; DWARF 4 (DWF4); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT5G05690.1); Has 31120 Blast hits to 31036 proteins in 1650 species: Archae - 61; Bacteria - 5303; Metazoa - 10591; Fungi - 5722; Plants - 7996; Viruses - 3; Other Eukaryotes - 1444 (source: NCBI BLink). & (reliability: 880.0) & (original description: no original description)


Gene families : OG_42_0000020 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000020_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_4726g0010
Cluster HCCA clusters: Cluster_57

Target Alias Description ECC score Gene Family Method Actions
Bradi1g69040 No alias Cytochrome P450 superfamily protein 0.03 Orthogroups_2024-Update
Glyma.14G059900 No alias Cytochrome P450 superfamily protein 0.02 Orthogroups_2024-Update
HORVU3Hr1G018860.3 No alias Unknown function 0.02 Orthogroups_2024-Update
Sopen06g017700 No alias Cytochrome P450 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005506 iron ion binding IEA InterProScan predictions
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterProScan predictions
MF GO:0020037 heme binding IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0006720 isoprenoid metabolic process IEP Predicted GO
MF GO:0008270 zinc ion binding IEP Predicted GO
BP GO:0008299 isoprenoid biosynthetic process IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009119 ribonucleoside metabolic process IEP Predicted GO
BP GO:0015969 guanosine tetraphosphate metabolic process IEP Predicted GO
BP GO:0033865 nucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0033875 ribonucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0034032 purine nucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0034035 purine ribonucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0042278 purine nucleoside metabolic process IEP Predicted GO
BP GO:0046128 purine ribonucleoside metabolic process IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001128 Cyt_P450 34 444
No external refs found!