Description : (q6f4f5|c724b_orysa : 533.0) Cytochrome P450 724B1 (EC 1.14.-.-) (OsDWARF11) (Dwarf protein 11) - Oryza sativa (Rice) & (at3g50660 : 440.0) Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.; DWARF 4 (DWF4); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT5G05690.1); Has 31120 Blast hits to 31036 proteins in 1650 species: Archae - 61; Bacteria - 5303; Metazoa - 10591; Fungi - 5722; Plants - 7996; Viruses - 3; Other Eukaryotes - 1444 (source: NCBI BLink). & (reliability: 880.0) & (original description: no original description)
Gene families : OG_42_0000020 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000020_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_4726g0010 | |
Cluster | HCCA clusters: Cluster_57 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Bradi1g69040 | No alias | Cytochrome P450 superfamily protein | 0.03 | Orthogroups_2024-Update | |
Glyma.14G059900 | No alias | Cytochrome P450 superfamily protein | 0.02 | Orthogroups_2024-Update | |
HORVU3Hr1G018860.3 | No alias | Unknown function | 0.02 | Orthogroups_2024-Update | |
Sopen06g017700 | No alias | Cytochrome P450 | 0.04 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005506 | iron ion binding | IEA | InterProScan predictions |
MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | InterProScan predictions |
MF | GO:0020037 | heme binding | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006720 | isoprenoid metabolic process | IEP | Predicted GO |
MF | GO:0008270 | zinc ion binding | IEP | Predicted GO |
BP | GO:0008299 | isoprenoid biosynthetic process | IEP | Predicted GO |
BP | GO:0009116 | nucleoside metabolic process | IEP | Predicted GO |
BP | GO:0009119 | ribonucleoside metabolic process | IEP | Predicted GO |
BP | GO:0015969 | guanosine tetraphosphate metabolic process | IEP | Predicted GO |
BP | GO:0033865 | nucleoside bisphosphate metabolic process | IEP | Predicted GO |
BP | GO:0033875 | ribonucleoside bisphosphate metabolic process | IEP | Predicted GO |
BP | GO:0034032 | purine nucleoside bisphosphate metabolic process | IEP | Predicted GO |
BP | GO:0034035 | purine ribonucleoside bisphosphate metabolic process | IEP | Predicted GO |
BP | GO:0042278 | purine nucleoside metabolic process | IEP | Predicted GO |
BP | GO:0046128 | purine ribonucleoside metabolic process | IEP | Predicted GO |
BP | GO:1901068 | guanosine-containing compound metabolic process | IEP | Predicted GO |
BP | GO:1901657 | glycosyl compound metabolic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001128 | Cyt_P450 | 34 | 444 |
No external refs found! |