Description : (at3g55360 : 452.0) Enoyl-CoA reductase is involved in all very long chain fatty acids (VLCFA) elongation reactions that are required for cuticular wax, storage lipid and sphingolipid metabolism. The protein is located in the ER, but in contrast to its yeast homolog TSC13 is not particularly enriched in the nuclear envelope-vacuole junction. Mutants in this gene show abnormal organ morphology and stem glossiness. Cells in all tissues are only about 1/3 of the size of wild type cells. The morphological changes are most likely to result from the reduction in the VLCFA content of sphingolipids. Mutants also show abnormalities in the endocytic membrane organization and transport.; ECERIFERUM 10 (CER10); FUNCTIONS IN: fatty acid elongase activity, trans-2-enoyl-CoA reductase (NADPH) activity, 3-oxo-5-alpha-steroid 4-dehydrogenase activity; INVOLVED IN: sphingolipid metabolic process, wax biosynthetic process; LOCATED IN: endoplasmic reticulum, fatty acid elongase complex, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104); BEST Arabidopsis thaliana protein match is: 3-oxo-5-alpha-steroid 4-dehydrogenase family protein (TAIR:AT5G16010.1); Has 1087 Blast hits to 1087 proteins in 269 species: Archae - 0; Bacteria - 73; Metazoa - 353; Fungi - 144; Plants - 184; Viruses - 0; Other Eukaryotes - 333 (source: NCBI BLink). & (reliability: 904.0) & (original description: no original description)
Gene families : OG_42_0006976 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006976_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_57254g0010 | |
Cluster | HCCA clusters: Cluster_200 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006629 | lipid metabolic process | IEA | InterProScan predictions |
MF | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004019 | adenylosuccinate synthase activity | IEP | Predicted GO |
MF | GO:0004175 | endopeptidase activity | IEP | Predicted GO |
MF | GO:0004190 | aspartic-type endopeptidase activity | IEP | Predicted GO |
MF | GO:0004222 | metalloendopeptidase activity | IEP | Predicted GO |
MF | GO:0004455 | ketol-acid reductoisomerase activity | IEP | Predicted GO |
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
MF | GO:0004568 | chitinase activity | IEP | Predicted GO |
CC | GO:0005575 | cellular_component | IEP | Predicted GO |
BP | GO:0006022 | aminoglycan metabolic process | IEP | Predicted GO |
BP | GO:0006026 | aminoglycan catabolic process | IEP | Predicted GO |
BP | GO:0006030 | chitin metabolic process | IEP | Predicted GO |
BP | GO:0006032 | chitin catabolic process | IEP | Predicted GO |
BP | GO:0006040 | amino sugar metabolic process | IEP | Predicted GO |
MF | GO:0008237 | metallopeptidase activity | IEP | Predicted GO |
BP | GO:0009056 | catabolic process | IEP | Predicted GO |
BP | GO:0009057 | macromolecule catabolic process | IEP | Predicted GO |
BP | GO:0009081 | branched-chain amino acid metabolic process | IEP | Predicted GO |
BP | GO:0009082 | branched-chain amino acid biosynthetic process | IEP | Predicted GO |
CC | GO:0016021 | integral component of membrane | IEP | Predicted GO |
BP | GO:0016485 | protein processing | IEP | Predicted GO |
MF | GO:0016787 | hydrolase activity | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
MF | GO:0016840 | carbon-nitrogen lyase activity | IEP | Predicted GO |
MF | GO:0016843 | amine-lyase activity | IEP | Predicted GO |
MF | GO:0016844 | strictosidine synthase activity | IEP | Predicted GO |
MF | GO:0016879 | ligase activity, forming carbon-nitrogen bonds | IEP | Predicted GO |
BP | GO:0016998 | cell wall macromolecule catabolic process | IEP | Predicted GO |
BP | GO:0017144 | drug metabolic process | IEP | Predicted GO |
CC | GO:0030014 | CCR4-NOT complex | IEP | Predicted GO |
CC | GO:0031224 | intrinsic component of membrane | IEP | Predicted GO |
BP | GO:0042737 | drug catabolic process | IEP | Predicted GO |
BP | GO:0044036 | cell wall macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0044248 | cellular catabolic process | IEP | Predicted GO |
CC | GO:0044425 | membrane part | IEP | Predicted GO |
BP | GO:0046348 | amino sugar catabolic process | IEP | Predicted GO |
BP | GO:0051604 | protein maturation | IEP | Predicted GO |
MF | GO:0070001 | aspartic-type peptidase activity | IEP | Predicted GO |
BP | GO:1901071 | glucosamine-containing compound metabolic process | IEP | Predicted GO |
BP | GO:1901072 | glucosamine-containing compound catabolic process | IEP | Predicted GO |
BP | GO:1901135 | carbohydrate derivative metabolic process | IEP | Predicted GO |
BP | GO:1901136 | carbohydrate derivative catabolic process | IEP | Predicted GO |
BP | GO:1901565 | organonitrogen compound catabolic process | IEP | Predicted GO |
BP | GO:1901575 | organic substance catabolic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001104 | 3-oxo-5_a-steroid_4-DH_C | 157 | 307 |
No external refs found! |