Description : (o24145|4cl1_tobac : 656.0) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (4-coumaroyl-CoA synthase 1) - Nicotiana tabacum (Common tobacco) & (at3g21240 : 613.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 2 (4CL2); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 1 (TAIR:AT1G51680.1); Has 86092 Blast hits to 78635 proteins in 3758 species: Archae - 1209; Bacteria - 54193; Metazoa - 3597; Fungi - 4717; Plants - 2816; Viruses - 1; Other Eukaryotes - 19559 (source: NCBI BLink). & (reliability: 1226.0) & (original description: no original description)
Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_633407g0010 | |
Cluster | HCCA clusters: Cluster_174 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Bradi3g37300 | No alias | 4-coumarate:CoA ligase 2 | 0.02 | Orthogroups_2024-Update | |
Bradi4g19947 | No alias | AMP-dependent synthetase and ligase family protein | 0.03 | Orthogroups_2024-Update | |
Brara.E02089.1 | No alias | p-coumarate | 0.02 | Orthogroups_2024-Update | |
Brara.E02090.1 | No alias | p-coumarate | 0.03 | Orthogroups_2024-Update | |
Brara.E02091.1 | No alias | p-coumarate | 0.03 | Orthogroups_2024-Update | |
Brara.F01460.1 | No alias | OPC-8 | 0.03 | Orthogroups_2024-Update | |
Brara.H02326.1 | No alias | OPC-8 | 0.03 | Orthogroups_2024-Update | |
LOC_Os08g34790 | No alias | AMP-binding domain containing protein, expressed | 0.03 | Orthogroups_2024-Update | |
MA_103893g0010 | No alias | (at1g20510 : 417.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.03 | Orthogroups_2024-Update | |
MA_10922g0010 | No alias | (at1g20510 : 573.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.03 | Orthogroups_2024-Update | |
MA_4881g0010 | No alias | (at1g20510 : 253.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.03 | Orthogroups_2024-Update | |
MA_5g0040 | No alias | (at4g05160 : 362.0) Encodes a peroxisomal protein... | 0.03 | Orthogroups_2024-Update | |
PSME_00010615-RA | No alias | (at1g20510 : 540.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.04 | Orthogroups_2024-Update | |
PSME_00041965-RA | No alias | (at1g20510 : 583.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.04 | Orthogroups_2024-Update | |
Potri.001G036900 | No alias | 4-coumarate:CoA ligase 2 | 0.04 | Orthogroups_2024-Update | |
Seita.1G065800.1 | No alias | p-coumarate | 0.04 | Orthogroups_2024-Update | |
Sobic.007G089900.1 | No alias | p-coumarate | 0.04 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003824 | catalytic activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004497 | monooxygenase activity | IEP | Predicted GO |
MF | GO:0004499 | N,N-dimethylaniline monooxygenase activity | IEP | Predicted GO |
MF | GO:0008236 | serine-type peptidase activity | IEP | Predicted GO |
MF | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | IEP | Predicted GO |
MF | GO:0016846 | carbon-sulfur lyase activity | IEP | Predicted GO |
MF | GO:0017171 | serine hydrolase activity | IEP | Predicted GO |
BP | GO:0019538 | protein metabolic process | IEP | Predicted GO |
MF | GO:0050660 | flavin adenine dinucleotide binding | IEP | Predicted GO |
MF | GO:0050662 | coenzyme binding | IEP | Predicted GO |
No external refs found! |