MA_633407g0010


Description : (o24145|4cl1_tobac : 656.0) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (4-coumaroyl-CoA synthase 1) - Nicotiana tabacum (Common tobacco) & (at3g21240 : 613.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 2 (4CL2); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 1 (TAIR:AT1G51680.1); Has 86092 Blast hits to 78635 proteins in 3758 species: Archae - 1209; Bacteria - 54193; Metazoa - 3597; Fungi - 4717; Plants - 2816; Viruses - 1; Other Eukaryotes - 19559 (source: NCBI BLink). & (reliability: 1226.0) & (original description: no original description)


Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_633407g0010
Cluster HCCA clusters: Cluster_174

Target Alias Description ECC score Gene Family Method Actions
Bradi3g37300 No alias 4-coumarate:CoA ligase 2 0.02 Orthogroups_2024-Update
Bradi4g19947 No alias AMP-dependent synthetase and ligase family protein 0.03 Orthogroups_2024-Update
Brara.E02089.1 No alias p-coumarate 0.02 Orthogroups_2024-Update
Brara.E02090.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Brara.E02091.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Brara.F01460.1 No alias OPC-8 0.03 Orthogroups_2024-Update
Brara.H02326.1 No alias OPC-8 0.03 Orthogroups_2024-Update
LOC_Os08g34790 No alias AMP-binding domain containing protein, expressed 0.03 Orthogroups_2024-Update
MA_103893g0010 No alias (at1g20510 : 417.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
MA_10922g0010 No alias (at1g20510 : 573.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
MA_4881g0010 No alias (at1g20510 : 253.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
MA_5g0040 No alias (at4g05160 : 362.0) Encodes a peroxisomal protein... 0.03 Orthogroups_2024-Update
PSME_00010615-RA No alias (at1g20510 : 540.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
PSME_00041965-RA No alias (at1g20510 : 583.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
Potri.001G036900 No alias 4-coumarate:CoA ligase 2 0.04 Orthogroups_2024-Update
Seita.1G065800.1 No alias p-coumarate 0.04 Orthogroups_2024-Update
Sobic.007G089900.1 No alias p-coumarate 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004497 monooxygenase activity IEP Predicted GO
MF GO:0004499 N,N-dimethylaniline monooxygenase activity IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
MF GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IEP Predicted GO
MF GO:0016846 carbon-sulfur lyase activity IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
MF GO:0050660 flavin adenine dinucleotide binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
InterPro domains Description Start Stop
IPR025110 AMP-bd_C 450 525
IPR000873 AMP-dep_Synth/Lig 33 441
No external refs found!