Description : (q6f4f5|c724b_orysa : 270.0) Cytochrome P450 724B1 (EC 1.14.-.-) (OsDWARF11) (Dwarf protein 11) - Oryza sativa (Rice) & (at3g50660 : 189.0) Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.; DWARF 4 (DWF4); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT5G05690.1); Has 31120 Blast hits to 31036 proteins in 1650 species: Archae - 61; Bacteria - 5303; Metazoa - 10591; Fungi - 5722; Plants - 7996; Viruses - 3; Other Eukaryotes - 1444 (source: NCBI BLink). & (reliability: 352.0) & (original description: no original description)
Gene families : OG_42_0000020 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000020_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_72115g0010 | |
Cluster | HCCA clusters: Cluster_295 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_27743 | No alias | abietadienolabietadienal oxidase | 0.04 | Orthogroups_2024-Update | |
A4A49_38884 | No alias | abscisic acid 8'-hydroxylase 1 | 0.03 | Orthogroups_2024-Update | |
At5g38970 | No alias | Cytochrome P450 85A1 [Source:UniProtKB/Swiss-Prot;Acc:Q9FMA5] | 0.03 | Orthogroups_2024-Update | |
At5g45340 | No alias | Abscisic acid 8'-hydroxylase 3... | 0.04 | Orthogroups_2024-Update | |
Brara.G03270.1 | No alias | EC_1.14 oxidoreductase acting on paired donor with... | 0.02 | Orthogroups_2024-Update | |
Glyma.07G212700 | No alias | cytochrome P450, family 707, subfamily A, polypeptide 4 | 0.02 | Orthogroups_2024-Update | |
Glyma.09G029400 | No alias | cytochrome P450, family 88, subfamily A, polypeptide 3 | 0.02 | Orthogroups_2024-Update | |
Glyma.14G082900 | No alias | cytochrome P450, family 707, subfamily A, polypeptide 4 | 0.02 | Orthogroups_2024-Update | |
Glyma.16G068100 | No alias | cytochrome P450, family 724, subfamily A, polypeptide 1 | 0.02 | Orthogroups_2024-Update | |
Glyma.18G028300 | No alias | Cytochrome P450 superfamily protein | 0.03 | Orthogroups_2024-Update | |
HORVU2Hr1G102260.2 | No alias | EC_1.14 oxidoreductase acting on paired donor with... | 0.02 | Orthogroups_2024-Update | |
HORVU3Hr1G018860.3 | No alias | Unknown function | 0.02 | Orthogroups_2024-Update | |
HORVU4Hr1G032830.3 | No alias | 6-deoxocastasterone 6-oxidase *(BR6OX) & EC_1.14... | 0.03 | Orthogroups_2024-Update | |
HORVU4Hr1G065440.16 | No alias | steroid 22-alpha-hydroxylase *(DWF4) & EC_1.14... | 0.02 | Orthogroups_2024-Update | |
LOC_Os07g33480 | No alias | cytochrome P450 domain containing protein, expressed | 0.02 | Orthogroups_2024-Update | |
MA_398469g0010 | No alias | "(at5g36110 : 234.0) member of CYP716A; ""cytochrome... | 0.04 | Orthogroups_2024-Update | |
MA_503753g0010 | No alias | "(at2g42850 : 301.0) member of CYP718; ""cytochrome... | 0.04 | Orthogroups_2024-Update | |
MA_78208g0010 | No alias | (at5g36130 : 136.0) Cytochrome P450 superfamily protein;... | 0.06 | Orthogroups_2024-Update | |
Mp1g04680.1 | No alias | Cytochrome P450 716B1 OS=Picea sitchensis... | 0.02 | Orthogroups_2024-Update | |
PSME_00023934-RA | No alias | "(at5g36110 : 315.0) member of CYP716A; ""cytochrome... | 0.03 | Orthogroups_2024-Update | |
PSME_00025038-RA | No alias | (at1g73340 : 355.0) Cytochrome P450 superfamily protein;... | 0.03 | Orthogroups_2024-Update | |
PSME_00035402-RA | No alias | (at1g73340 : 380.0) Cytochrome P450 superfamily protein;... | 0.03 | Orthogroups_2024-Update | |
Potri.001G341000 | No alias | cytochrome P450, family 724, subfamily A, polypeptide 1 | 0.03 | Orthogroups_2024-Update | |
Potri.002G060700 | No alias | cytochrome P450, family 718 | 0.03 | Orthogroups_2024-Update | |
Potri.004G017800 | No alias | cytochrome P450, family 716, subfamily A, polypeptide 1 | 0.03 | Orthogroups_2024-Update | |
Potri.014G171700 | No alias | cytochrome P450, family 724, subfamily A, polypeptide 1 | 0.02 | Orthogroups_2024-Update | |
Seita.2G229900.1 | No alias | abscisic acid hydroxylase & EC_1.14 oxidoreductase... | 0.03 | Orthogroups_2024-Update | |
Seita.5G139200.1 | No alias | 3-epi-6-deoxocathasterone 23-monooxygenase & EC_1.14... | 0.02 | Orthogroups_2024-Update | |
Sobic.001G147500.1 | No alias | EC_1.14 oxidoreductase acting on paired donor with... | 0.03 | Orthogroups_2024-Update | |
Sobic.001G164100.1 | No alias | EC_1.14 oxidoreductase acting on paired donor with... | 0.02 | Orthogroups_2024-Update | |
Sobic.001G172400.1 | No alias | 6-deoxocastasterone 6-oxidase *(BR6OX) & EC_1.14... | 0.02 | Orthogroups_2024-Update | |
Sobic.004G283900.1 | No alias | EC_1.14 oxidoreductase acting on paired donor with... | 0.04 | Orthogroups_2024-Update | |
Sobic.007G156300.1 | No alias | abscisic acid hydroxylase & EC_1.14 oxidoreductase... | 0.02 | Orthogroups_2024-Update | |
Sobic.010G007700.1 | No alias | ent-kaurene oxidase *(KAO) & EC_1.14 oxidoreductase... | 0.03 | Orthogroups_2024-Update | |
Solyc02g084740 | No alias | Cytochrome P450 (AHRD V3.3 *** D7MBI4_ARALL) | 0.03 | Orthogroups_2024-Update | |
Solyc02g089160 | No alias | dwarf | 0.02 | Orthogroups_2024-Update | |
Solyc05g021390 | No alias | Cytochrome P450 (AHRD V3.3 *** A0A161ABB0_OCIBA) | 0.02 | Orthogroups_2024-Update | |
Solyc08g007050 | No alias | Cytochrome P450 (AHRD V3.3 *** A0A0B0PH67_GOSAR) | 0.02 | Orthogroups_2024-Update | |
Sopen01g018010 | No alias | hypothetical protein | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005506 | iron ion binding | IEA | InterProScan predictions |
MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | InterProScan predictions |
MF | GO:0020037 | heme binding | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | IEP | Predicted GO |
BP | GO:0000956 | nuclear-transcribed mRNA catabolic process | IEP | Predicted GO |
MF | GO:0003885 | D-arabinono-1,4-lactone oxidase activity | IEP | Predicted GO |
MF | GO:0004451 | isocitrate lyase activity | IEP | Predicted GO |
MF | GO:0004601 | peroxidase activity | IEP | Predicted GO |
MF | GO:0004867 | serine-type endopeptidase inhibitor activity | IEP | Predicted GO |
MF | GO:0005094 | Rho GDP-dissociation inhibitor activity | IEP | Predicted GO |
CC | GO:0005737 | cytoplasm | IEP | Predicted GO |
CC | GO:0005787 | signal peptidase complex | IEP | Predicted GO |
BP | GO:0006401 | RNA catabolic process | IEP | Predicted GO |
BP | GO:0006402 | mRNA catabolic process | IEP | Predicted GO |
BP | GO:0006465 | signal peptide processing | IEP | Predicted GO |
BP | GO:0006950 | response to stress | IEP | Predicted GO |
BP | GO:0006979 | response to oxidative stress | IEP | Predicted GO |
BP | GO:0009611 | response to wounding | IEP | Predicted GO |
MF | GO:0016209 | antioxidant activity | IEP | Predicted GO |
BP | GO:0016485 | protein processing | IEP | Predicted GO |
MF | GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | IEP | Predicted GO |
MF | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | IEP | Predicted GO |
MF | GO:0016684 | oxidoreductase activity, acting on peroxide as acceptor | IEP | Predicted GO |
MF | GO:0016833 | oxo-acid-lyase activity | IEP | Predicted GO |
MF | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor | IEP | Predicted GO |
BP | GO:0046834 | lipid phosphorylation | IEP | Predicted GO |
BP | GO:0046854 | phosphatidylinositol phosphorylation | IEP | Predicted GO |
MF | GO:0050660 | flavin adenine dinucleotide binding | IEP | Predicted GO |
MF | GO:0050662 | coenzyme binding | IEP | Predicted GO |
BP | GO:0050896 | response to stimulus | IEP | Predicted GO |
BP | GO:0051604 | protein maturation | IEP | Predicted GO |
CC | GO:1905368 | peptidase complex | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001128 | Cyt_P450 | 73 | 300 |
No external refs found! |