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  5. MA_76459g0010

MA_76459g0010


Description : (at1g68760 : 131.0) Encodes a cytosol-localized nudix hydrolase that hydrolyzes 8-oxo-(d)GTP to its monophosphate form. This protective mechanism prevents the misincorporation of these oxidized nucleotides into DNA and RNA. NUDX1 also has a low level of dihydroneopterin triphosphate pyrophosphatase activity in vitro and may participate in the folate synthesis pathway.; nudix hydrolase 1 (NUDX1); FUNCTIONS IN: hydrolase activity, dihydroneopterin triphosphate pyrophosphohydrolase activity, 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; INVOLVED IN: response to DNA damage stimulus; LOCATED IN: cytosol; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase (InterPro:IPR020476), NUDIX hydrolase, conserved site (InterPro:IPR020084), NUDIX hydrolase domain (InterPro:IPR000086); Has 6319 Blast hits to 6317 proteins in 1575 species: Archae - 191; Bacteria - 5327; Metazoa - 193; Fungi - 66; Plants - 51; Viruses - 14; Other Eukaryotes - 477 (source: NCBI BLink). & (reliability: 262.0) & (original description: no original description)


Gene families : OG_42_0008511 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0008511_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_76459g0010
Cluster HCCA clusters: Cluster_260


Type GO Term Name Evidence Source
MF GO:0016787 hydrolase activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003690 double-stranded DNA binding IEP Predicted GO
MF GO:0003885 D-arabinono-1,4-lactone oxidase activity IEP Predicted GO
MF GO:0004427 inorganic diphosphatase activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
CC GO:0005741 mitochondrial outer membrane IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
MF GO:0016597 amino acid binding IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016743 carboxyl- or carbamoyltransferase activity IEP Predicted GO
MF GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor IEP Predicted GO
CC GO:0019867 outer membrane IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
CC GO:0031090 organelle membrane IEP Predicted GO
MF GO:0031406 carboxylic acid binding IEP Predicted GO
CC GO:0031966 mitochondrial membrane IEP Predicted GO
CC GO:0031968 organelle outer membrane IEP Predicted GO
MF GO:0043177 organic acid binding IEP Predicted GO
CC GO:0044429 mitochondrial part IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
CC GO:0098588 bounding membrane of organelle IEP Predicted GO
CC GO:0098805 whole membrane IEP Predicted GO
InterPro domains Description Start Stop
IPR000086 NUDIX_hydrolase_dom 28 141
No external refs found!