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Description : (q8w013|comt1_catro : 180.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 174.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 348.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Picea release: MA_8268940g0010 | |
| Cluster | HCCA clusters: Cluster_53 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| At1g21130 | No alias | Indole glucosinolate O-methyltransferase 4... | 0.03 | Orthogroups_2024-Update | |
| At5g54160 | No alias | Flavone 3'-O-methyltransferase 1... | 0.03 | Orthogroups_2024-Update | |
| Brara.K00607.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| GRMZM2G106172 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| Glyma.20G176100 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
| HORVU6Hr1G090510.2 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| MA_74925g0020 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
| MA_86945g0010 | No alias | (at5g54160 : 94.7) A caffeic acid/5-hydroxyferulic acid... | 0.05 | Orthogroups_2024-Update | |
| PSME_00041945-RA | No alias | (q8w013|comt1_catro : 154.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| PSME_00052715-RA | No alias | (p28002|comt1_medsa : 235.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| Potri.009G139800 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Seita.6G174800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
| Seita.8G210100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.005G216100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.005G216200.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.007G058400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Sobic.009G198000.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Solyc06g007960 | No alias | Caffeic O-methyltransferase (AHRD V3.3 *** A0A068FLE8_PUNGR) | 0.03 | Orthogroups_2024-Update | |
| Solyc10g047520 | No alias | LOW QUALITY:O-methyltransferase (AHRD V3.3 *-* Q6VMV7_MENPI) | 0.03 | Orthogroups_2024-Update | |
| Sopen10g003990 | No alias | O-methyltransferase | 0.03 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
| MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004601 | peroxidase activity | IEP | Predicted GO |
| BP | GO:0006766 | vitamin metabolic process | IEP | Predicted GO |
| BP | GO:0006767 | water-soluble vitamin metabolic process | IEP | Predicted GO |
| BP | GO:0006771 | riboflavin metabolic process | IEP | Predicted GO |
| BP | GO:0006979 | response to oxidative stress | IEP | Predicted GO |
| MF | GO:0008703 | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity | IEP | Predicted GO |
| BP | GO:0009110 | vitamin biosynthetic process | IEP | Predicted GO |
| BP | GO:0009231 | riboflavin biosynthetic process | IEP | Predicted GO |
| MF | GO:0016209 | antioxidant activity | IEP | Predicted GO |
| MF | GO:0016684 | oxidoreductase activity, acting on peroxide as acceptor | IEP | Predicted GO |
| BP | GO:0042364 | water-soluble vitamin biosynthetic process | IEP | Predicted GO |
| BP | GO:0042726 | flavin-containing compound metabolic process | IEP | Predicted GO |
| BP | GO:0042727 | flavin-containing compound biosynthetic process | IEP | Predicted GO |
| No external refs found! |