MA_916238g0010

Description : (p29449|trxh1_tobac : 147.0) Thioredoxin H-type 1 (TRX-H1) - Nicotiana tabacum (Common tobacco) & (at3g51030 : 144.0) encodes a cytosolic thioredoxin that reduces disulfide bridges of target proteins by the reversible formation of a disulfide bridge between two neighboring Cys residues present in the active site. Thioredoxins have been found to regulate a variety of biological reactions in prokaryotic and eukaryotic cells.; thioredoxin H-type 1 (TRX1); FUNCTIONS IN: oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; INVOLVED IN: cell redox homeostasis; LOCATED IN: cytosol; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin, core (InterPro:IPR015467), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: thioredoxin H-type 5 (TAIR:AT1G45145.1); Has 18017 Blast hits to 17697 proteins in 2965 species: Archae - 232; Bacteria - 9905; Metazoa - 1876; Fungi - 909; Plants - 1960; Viruses - 5; Other Eukaryotes - 3130 (source: NCBI BLink). & (reliability: 288.0) & (original description: no original description)

Gene families : OG_42_0000297 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000297_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_916238g0010
Cluster	HCCA clusters: Cluster_174

Target	Alias	Description	ECC score	Gene Family Method
A4A49_13313	No alias	thioredoxin h2	0.02	Orthogroups_2024-Update
A4A49_40359	No alias	thioredoxin h2	0.03	Orthogroups_2024-Update
Glyma.09G273200	No alias	thioredoxin H-type 9	0.02	Orthogroups_2024-Update
LOC_Os03g58630	No alias	thioredoxin, putative, expressed	0.02	Orthogroups_2024-Update
Pp1s21_318V6	No alias	thioredoxin h	0.05	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0019725	cellular homeostasis	None	Extended
BP	GO:0042592	homeostatic process	None	Extended
BP	GO:0045454	cell redox homeostasis	IEA	InterProScan predictions
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000813	ESCRT I complex	IEP	Predicted GO
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0003849	3-deoxy-7-phosphoheptulonate synthase activity	IEP	Predicted GO
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006090	pyruvate metabolic process	IEP	Predicted GO
MF	GO:0008047	enzyme activator activity	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008171	O-methyltransferase activity	IEP	Predicted GO
MF	GO:0008198	ferrous iron binding	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
BP	GO:0008654	phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009073	aromatic amino acid family biosynthetic process	IEP	Predicted GO
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Predicted GO
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Predicted GO
MF	GO:0019842	vitamin binding	IEP	Predicted GO
MF	GO:0030170	pyridoxal phosphate binding	IEP	Predicted GO
BP	GO:0032509	endosome transport via multivesicular body sorting pathway	IEP	Predicted GO
CC	GO:0036452	ESCRT complex	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0044440	endosomal part	IEP	Predicted GO
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
MF	GO:0070279	vitamin B6 binding	IEP	Predicted GO
BP	GO:0071985	multivesicular body sorting pathway	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013766	Thioredoxin_domain	10	107

External Links

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MA_916238g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation