evm.model.contig_2085.12


Description : (at5g23630 : 753.0) A member of the eukaryotic type V subfamily (P5) of P-type ATPase cation pumps; MIA is most similar to the human P5 ATPase ATY2(44% identity) and to Spf1p from S. cerevisiae (41% identity). Highly abundant in the endoplasmic reticulum and small vesicles of developing pollen grains and tapetum cells. T-DNA insertional mutants of MIA suffer from imbalances in cation homeostasis and exhibit a severe reduction in fertility. Mutant microspores fail to separate from tetrads and pollen grains are fragile with an abnormal morphology and altered cell wall structure. MIA is also named PDR2 and was shown to be required for proper expression of SCARECROW (SCR), a key regulator of root patterning, and for stem-cell maintenance in Pi-deprived roots.; phosphate deficiency response 2 (PDR2); FUNCTIONS IN: cation-transporting ATPase activity; INVOLVED IN: in 6 processes; LOCATED IN: endoplasmic reticulum, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, unknown pump specificity (type V) (InterPro:IPR006544), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: calcium ATPase 2 (TAIR:AT4G37640.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1506.0) & (original description: no original description)


Gene families : OG_42_0005645 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005645_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_2085.12
Cluster HCCA clusters: Cluster_65


Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0000213 tRNA-intron endonuclease activity IEP Predicted GO
BP GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation IEP Predicted GO
MF GO:0003674 molecular_function IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003690 double-stranded DNA binding IEP Predicted GO
MF GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity IEP Predicted GO
MF GO:0003951 NAD+ kinase activity IEP Predicted GO
MF GO:0004549 tRNA-specific ribonuclease activity IEP Predicted GO
MF GO:0004852 uroporphyrinogen-III synthase activity IEP Predicted GO
CC GO:0005669 transcription factor TFIID complex IEP Predicted GO
CC GO:0005732 small nucleolar ribonucleoprotein complex IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006352 DNA-templated transcription, initiation IEP Predicted GO
BP GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006741 NADP biosynthetic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
BP GO:0008033 tRNA processing IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
MF GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019208 phosphatase regulator activity IEP Predicted GO
MF GO:0019211 phosphatase activator activity IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
CC GO:0030915 Smc5-Smc6 complex IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
BP GO:0032774 RNA biosynthetic process IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
CC GO:0034457 Mpp10 complex IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
CC GO:0044452 nucleolar part IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
MF GO:0061505 DNA topoisomerase II activity IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
CC GO:0106068 SUMO ligase complex IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!