Description : (at1g47290 : 151.0) Encodes an enzyme with 3β-hydroxysteroid dehydrogenase/C4-decarboxylase activity <i>in vitro</i>. The activity of the enzyme was determined using microsomal extracts of yeast overexpressing the <i>Arabidopsis</i> gene. Cytosolic fractions failed to be associated to the activity, leading to the speculation that the enzyme is membrane-bound.; 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 (3BETAHSD/D1); FUNCTIONS IN: 3-beta-hydroxy-delta5-steroid dehydrogenase activity, sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; INVOLVED IN: steroid biosynthetic process, metabolic process; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD(P)-binding domain (InterPro:IPR016040), 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225); BEST Arabidopsis thaliana protein match is: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 (TAIR:AT2G26260.1); Has 24445 Blast hits to 24432 proteins in 2873 species: Archae - 619; Bacteria - 15430; Metazoa - 691; Fungi - 529; Plants - 1560; Viruses - 132; Other Eukaryotes - 5484 (source: NCBI BLink). & (reliability: 302.0) & (original description: no original description)
Gene families : OG_42_0001400 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001400_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_2199.4 | |
Cluster | HCCA clusters: Cluster_11 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Bradi1g60280 | No alias | 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 | 0.01 | Orthogroups_2024-Update | |
Cre12.g518650 | No alias | 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 | 0.02 | Orthogroups_2024-Update | |
Glyma.03G002500 | No alias | 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 | 0.01 | Orthogroups_2024-Update | |
Glyma.07G107800 | No alias | 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 | 0.01 | Orthogroups_2024-Update | |
Kfl00162_0200 | kfl00162_0200_v1.1 | (at2g26260 : 303.0) Encodes an enzyme with... | 0.03 | Orthogroups_2024-Update | |
Sopen02g026330 | No alias | 3-beta hydroxysteroid dehydrogenase/isomerase family | 0.02 | Orthogroups_2024-Update | |
evm.model.tig00000215.116 | No alias | (at1g47290 : 240.0) Encodes an enzyme with... | 0.01 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | IEA | InterProScan predictions |
BP | GO:0006694 | steroid biosynthetic process | IEA | InterProScan predictions |
MF | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000272 | polysaccharide catabolic process | IEP | Predicted GO |
MF | GO:0004478 | methionine adenosyltransferase activity | IEP | Predicted GO |
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
MF | GO:0005506 | iron ion binding | IEP | Predicted GO |
BP | GO:0005976 | polysaccharide metabolic process | IEP | Predicted GO |
BP | GO:0006486 | protein glycosylation | IEP | Predicted GO |
BP | GO:0006556 | S-adenosylmethionine biosynthetic process | IEP | Predicted GO |
BP | GO:0009240 | isopentenyl diphosphate biosynthetic process | IEP | Predicted GO |
MF | GO:0016160 | amylase activity | IEP | Predicted GO |
MF | GO:0016161 | beta-amylase activity | IEP | Predicted GO |
CC | GO:0016272 | prefoldin complex | IEP | Predicted GO |
MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEP | Predicted GO |
MF | GO:0016725 | oxidoreductase activity, acting on CH or CH2 groups | IEP | Predicted GO |
MF | GO:0016726 | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor | IEP | Predicted GO |
MF | GO:0016746 | transferase activity, transferring acyl groups | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
MF | GO:0016854 | racemase and epimerase activity | IEP | Predicted GO |
MF | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives | IEP | Predicted GO |
BP | GO:0019288 | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway | IEP | Predicted GO |
MF | GO:0020037 | heme binding | IEP | Predicted GO |
MF | GO:0043169 | cation binding | IEP | Predicted GO |
BP | GO:0043413 | macromolecule glycosylation | IEP | Predicted GO |
BP | GO:0046490 | isopentenyl diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0046500 | S-adenosylmethionine metabolic process | IEP | Predicted GO |
MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
MF | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | IEP | Predicted GO |
BP | GO:0050992 | dimethylallyl diphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0050993 | dimethylallyl diphosphate metabolic process | IEP | Predicted GO |
MF | GO:0051745 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity | IEP | Predicted GO |
BP | GO:0070085 | glycosylation | IEP | Predicted GO |
MF | GO:0070569 | uridylyltransferase activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR002225 | 3Beta_OHSteriod_DH/Estase | 18 | 269 |
No external refs found! |