evm.model.contig_2358.3

Description : (p56336|if5a4_soltu : 162.0) Eukaryotic translation initiation factor 5A-4 (eIF-5A-4) (eIF-4D) - Solanum tuberosum (Potato) & (at1g69410 : 158.0) Encodes eIF5A-2, a putative eukaryotic translation initiation factor. There are three eIF5A coding genes in Arabidopsis: eIF5A-1/At1g13950, eIF5A-2/At1g26630 and eIF5A-3/At1g69410.; eukaryotic elongation factor 5A-3 (ELF5A-3); FUNCTIONS IN: ribosome binding, RNA binding, translation elongation factor activity, translation initiation factor activity; INVOLVED IN: translational initiation, translational frameshifting, positive regulation of translational termination, peptidyl-lysine modification to hypusine, positive regulation of translational elongation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Translation elongation factor, IF5A, hypusine site (InterPro:IPR019769), Translation protein SH3-like, subgroup (InterPro:IPR014722), Translation elongation factor, IF5A (InterPro:IPR001884), Translation elongation factor, IF5A C-terminal (InterPro:IPR020189), Translation protein SH3-like (InterPro:IPR008991), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), KOW (InterPro:IPR005824); BEST Arabidopsis thaliana protein match is: eukaryotic elongation factor 5A-1 (TAIR:AT1G13950.1); Has 1331 Blast hits to 1330 proteins in 408 species: Archae - 255; Bacteria - 0; Metazoa - 363; Fungi - 252; Plants - 260; Viruses - 0; Other Eukaryotes - 201 (source: NCBI BLink). & (reliability: 316.0) & (original description: no original description)

Gene families : OG_42_0001304 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001304_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Porphyridium release: evm.model.contig_2358.3
Cluster	HCCA clusters: Cluster_75

Target	Alias	Description	ECC score	Gene Family Method
A4A49_13934	No alias	eukaryotic translation initiation factor 5a-12	0.02	Orthogroups_2024-Update
A4A49_55854	No alias	eukaryotic translation initiation factor 5a-2	0.02	Orthogroups_2024-Update
Glyma.05G024200	No alias	eukaryotic elongation factor 5A-1	0.03	Orthogroups_2024-Update
Glyma.17G103100	No alias	eukaryotic elongation factor 5A-1	0.05	Orthogroups_2024-Update
HORVU5Hr1G028360.3	No alias	poly-P/G elongation factor *(eEF5/eIF5A))	0.01	Orthogroups_2024-Update
LOC_Os12g32240	No alias	eukaryotic translation initiation factor 5A, putative, expressed	0.04	Orthogroups_2024-Update
PSME_00024028-RA	No alias	(p24922\|if5a2_nicpl : 134.0) Eukaryotic translation...	0.04	Orthogroups_2024-Update
Solyc01g011000	No alias	Eukaryotic translation initiation factor 5A (AHRD V3.3...	0.03	Orthogroups_2024-Update
Sopen01g006960	No alias	Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold	0.02	Orthogroups_2024-Update
Sopen04g001530	No alias	Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold	0.09	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	InterProScan predictions
MF	GO:0003746	translation elongation factor activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006414	translational elongation	None	Extended
BP	GO:0006417	regulation of translation	None	Extended
BP	GO:0006448	regulation of translational elongation	None	Extended
BP	GO:0006449	regulation of translational termination	None	Extended
BP	GO:0006452	translational frameshifting	IEA	InterProScan predictions
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009891	positive regulation of biosynthetic process	None	Extended
BP	GO:0009893	positive regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010557	positive regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010604	positive regulation of macromolecule metabolic process	None	Extended
BP	GO:0010608	posttranscriptional regulation of gene expression	None	Extended
BP	GO:0010628	positive regulation of gene expression	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031325	positive regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0031328	positive regulation of cellular biosynthetic process	None	Extended
BP	GO:0032268	regulation of cellular protein metabolic process	None	Extended
BP	GO:0032270	positive regulation of cellular protein metabolic process	None	Extended
BP	GO:0034248	regulation of cellular amide metabolic process	None	Extended
BP	GO:0034250	positive regulation of cellular amide metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0043021	ribonucleoprotein complex binding	None	Extended
MF	GO:0043022	ribosome binding	IEA	InterProScan predictions
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043243	positive regulation of protein complex disassembly	None	Extended
BP	GO:0043244	regulation of protein complex disassembly	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
MF	GO:0044877	protein-containing complex binding	None	Extended
BP	GO:0045727	positive regulation of translation	None	Extended
BP	GO:0045901	positive regulation of translational elongation	IEA	InterProScan predictions
BP	GO:0045905	positive regulation of translational termination	IEA	InterProScan predictions
BP	GO:0048518	positive regulation of biological process	None	Extended
BP	GO:0048522	positive regulation of cellular process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051130	positive regulation of cellular component organization	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0051247	positive regulation of protein metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000213	tRNA-intron endonuclease activity	IEP	Predicted GO
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	IEP	Predicted GO
MF	GO:0003725	double-stranded RNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004549	tRNA-specific ribonuclease activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004827	proline-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005741	mitochondrial outer membrane	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006433	prolyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
MF	GO:0008097	5S rRNA binding	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Predicted GO
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters	IEP	Predicted GO
MF	GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
MF	GO:0019843	rRNA binding	IEP	Predicted GO
CC	GO:0019867	outer membrane	IEP	Predicted GO
CC	GO:0031090	organelle membrane	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
CC	GO:0031968	organelle outer membrane	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044429	mitochondrial part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
CC	GO:0098588	bounding membrane of organelle	IEP	Predicted GO
CC	GO:0098805	whole membrane	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR020189	Transl_elong_IF5A_C	87	156

External Links

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evm.model.contig_2358.3

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation