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  5. evm.model.contig_2503.2

evm.model.contig_2503.2


Description : "(at5g56290 : 222.0) Encodes the peroxisomal targeting signal type 1 receptor that facilitates peroxisomal protein translocation. It recognizes proteins with the PTS1 consensus sequence (tripeptide SKL or a conserved variant) at the extreme C terminus. The protein has several domains, including C-terminal tetratricopeptide repeat motifs which act in binding the C-terminal ""SKL"" targeting signal. The mechanism of transport has been worked out in other organisms: The receptor recognizes and binds cytosolic PTS1-containing proteins. The PEX5-PTS1 complex binds a PEX14/PEX13 receptor complex at the peroxisome membrane and is translocated into the peroxisome matrix in a process dependent on PEX2,PEX10, and PEX12. In the peroxisome matrix, PEX5 releases its cargo and is recycled to the cytosol in a process dependent on PEX1, PEX4, PEX6 and PEX22. It is also involved, in conjunction with PEX7, in PTS1- and PTS2-dependent peroxisomal protein import. RNAi experiments suggest that PEX5 is necessary for the maintenance of both glyoxysomal and leaf peroxisomal functions.; peroxin 5 (PEX5); CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G11540.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (gnl|cdd|68872 : 142.0) no description available & (gnl|cdd|39774 : 85.9) no description available & (reliability: 444.0) & (original description: no original description)"


Gene families : OG_42_0006395 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006395_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_2503.2
Cluster HCCA clusters: Cluster_37

Target Alias Description ECC score Gene Family Method Actions
Bradi3g39510 No alias peroxin 5 0.01 Orthogroups_2024-Update
Sobic.007G217000.1 No alias component *(Pex5) of cargo-receptor system 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
CC GO:0000123 histone acetyltransferase complex IEP Predicted GO
CC GO:0000124 SAGA complex IEP Predicted GO
CC GO:0000139 Golgi membrane IEP Predicted GO
BP GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation IEP Predicted GO
MF GO:0003700 DNA-binding transcription factor activity IEP Predicted GO
MF GO:0003713 transcription coactivator activity IEP Predicted GO
CC GO:0005779 integral component of peroxisomal membrane IEP Predicted GO
BP GO:0006352 DNA-templated transcription, initiation IEP Predicted GO
BP GO:0006355 regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation IEP Predicted GO
BP GO:0006405 RNA export from nucleus IEP Predicted GO
BP GO:0006406 mRNA export from nucleus IEP Predicted GO
BP GO:0006906 vesicle fusion IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
MF GO:0008146 sulfotransferase activity IEP Predicted GO
BP GO:0009889 regulation of biosynthetic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0010468 regulation of gene expression IEP Predicted GO
BP GO:0010556 regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
BP GO:0015931 nucleobase-containing compound transport IEP Predicted GO
CC GO:0016021 integral component of membrane IEP Predicted GO
BP GO:0016050 vesicle organization IEP Predicted GO
BP GO:0016559 peroxisome fission IEP Predicted GO
MF GO:0016782 transferase activity, transferring sulfur-containing groups IEP Predicted GO
MF GO:0016987 sigma factor activity IEP Predicted GO
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0019222 regulation of metabolic process IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
CC GO:0031090 organelle membrane IEP Predicted GO
CC GO:0031224 intrinsic component of membrane IEP Predicted GO
CC GO:0031231 intrinsic component of peroxisomal membrane IEP Predicted GO
CC GO:0031248 protein acetyltransferase complex IEP Predicted GO
CC GO:0031300 intrinsic component of organelle membrane IEP Predicted GO
CC GO:0031301 integral component of organelle membrane IEP Predicted GO
BP GO:0031323 regulation of cellular metabolic process IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031326 regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0031965 nuclear membrane IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
CC GO:0044438 microbody part IEP Predicted GO
CC GO:0044439 peroxisomal part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
BP GO:0045893 positive regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0048280 vesicle fusion with Golgi apparatus IEP Predicted GO
BP GO:0048284 organelle fusion IEP Predicted GO
BP GO:0048285 organelle fission IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0048878 chemical homeostasis IEP Predicted GO
BP GO:0050657 nucleic acid transport IEP Predicted GO
BP GO:0050658 RNA transport IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0051028 mRNA transport IEP Predicted GO
BP GO:0051168 nuclear export IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051171 regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051236 establishment of RNA localization IEP Predicted GO
BP GO:0051252 regulation of RNA metabolic process IEP Predicted GO
BP GO:0051254 positive regulation of RNA metabolic process IEP Predicted GO
BP GO:0055088 lipid homeostasis IEP Predicted GO
BP GO:0060255 regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0061025 membrane fusion IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
CC GO:0070461 SAGA-type complex IEP Predicted GO
BP GO:0080090 regulation of primary metabolic process IEP Predicted GO
BP GO:0090174 organelle membrane fusion IEP Predicted GO
CC GO:0098588 bounding membrane of organelle IEP Predicted GO
MF GO:0140110 transcription regulator activity IEP Predicted GO
CC GO:1902493 acetyltransferase complex IEP Predicted GO
BP GO:1902680 positive regulation of RNA biosynthetic process IEP Predicted GO
BP GO:1903506 regulation of nucleic acid-templated transcription IEP Predicted GO
BP GO:1903508 positive regulation of nucleic acid-templated transcription IEP Predicted GO
CC GO:1905368 peptidase complex IEP Predicted GO
BP GO:2000112 regulation of cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:2001141 regulation of RNA biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR019734 TPR_repeat 648 678
No external refs found!