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- evm.model.contig_2562.2
evm.model.contig_2562.2
Description : (p93648|lonh2_maize : 671.0) Lon protease homolog 2, mitochondrial precursor (EC 3.4.21.-) - Zea mays (Maize) & (at5g26860 : 647.0) Encodes a member of the Lon protease-like proteins (Lon1/At5g26860, Lon2/At5g47040, Lon3/At3g05780, Lon4/At3g05790). Lon is a multifunctional ATP-dependent protease which exists in bacteria, archaea and within organelles in eukaryotic cells. Lon proteases are responsible for the degradation of abnormal, damaged and unstable proteins.; lon protease 1 (LON1); FUNCTIONS IN: serine-type peptidase activity, protein binding, ATP-dependent peptidase activity, ATP binding; INVOLVED IN: proteolysis; LOCATED IN: cytosol, mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), Peptidase S16, active site (InterPro:IPR008268), Peptidase S16, ATP-dependent protease La (InterPro:IPR004815), Peptidase S16, lon N-terminal (InterPro:IPR003111), Peptidase S16, Lon C-terminal (InterPro:IPR008269), ATPase, AAA+ type, core (InterPro:IPR003593), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Peptidase S16, Lon protease, C-terminal (InterPro:IPR001984); BEST Arabidopsis thaliana protein match is: lon protease 4 (TAIR:AT3G05790.1); Has 18238 Blast hits to 18056 proteins in 2534 species: Archae - 547; Bacteria - 9804; Metazoa - 746; Fungi - 600; Plants - 445; Viruses - 7; Other Eukaryotes - 6089 (source: NCBI BLink). & (reliability: 1294.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Porphyridium release: evm.model.contig_2562.2 | |
| Cluster | HCCA clusters: Cluster_60 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| 141788 | No alias | lon protease 2 | 0.02 | Orthogroups_2024-Update | |
| 444435 | No alias | lon protease 2 | 0.02 | Orthogroups_2024-Update | |
| HORVU2Hr1G016000.6 | No alias | LON-type protease | 0.02 | Orthogroups_2024-Update | |
| Kfl00486_0040 | kfl00486_0040_v1.1 | (at5g26860 : 352.0) Encodes a member of the Lon... | 0.02 | Orthogroups_2024-Update | |
| Solyc10g024300 | No alias | No description available | 0.03 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0000166 | nucleotide binding | None | Extended |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0003824 | catalytic activity | None | Extended |
| MF | GO:0004175 | endopeptidase activity | None | Extended |
| MF | GO:0004176 | ATP-dependent peptidase activity | IEA | InterProScan predictions |
| MF | GO:0004252 | serine-type endopeptidase activity | IEA | InterProScan predictions |
| MF | GO:0005488 | binding | None | Extended |
| MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
| BP | GO:0006508 | proteolysis | IEA | InterProScan predictions |
| BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
| MF | GO:0008144 | drug binding | None | Extended |
| BP | GO:0008150 | biological_process | None | Extended |
| BP | GO:0008152 | metabolic process | None | Extended |
| MF | GO:0008233 | peptidase activity | None | Extended |
| MF | GO:0008236 | serine-type peptidase activity | None | Extended |
| MF | GO:0016462 | pyrophosphatase activity | None | Extended |
| MF | GO:0016787 | hydrolase activity | None | Extended |
| MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | None | Extended |
| MF | GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | None | Extended |
| MF | GO:0016887 | ATPase activity | None | Extended |
| MF | GO:0017076 | purine nucleotide binding | None | Extended |
| MF | GO:0017111 | nucleoside-triphosphatase activity | None | Extended |
| MF | GO:0017171 | serine hydrolase activity | None | Extended |
| BP | GO:0019538 | protein metabolic process | None | Extended |
| MF | GO:0030554 | adenyl nucleotide binding | None | Extended |
| MF | GO:0032553 | ribonucleotide binding | None | Extended |
| MF | GO:0032555 | purine ribonucleotide binding | None | Extended |
| MF | GO:0032559 | adenyl ribonucleotide binding | None | Extended |
| MF | GO:0035639 | purine ribonucleoside triphosphate binding | None | Extended |
| MF | GO:0036094 | small molecule binding | None | Extended |
| MF | GO:0042623 | ATPase activity, coupled | None | Extended |
| MF | GO:0043167 | ion binding | None | Extended |
| MF | GO:0043168 | anion binding | None | Extended |
| BP | GO:0043170 | macromolecule metabolic process | None | Extended |
| BP | GO:0044238 | primary metabolic process | None | Extended |
| MF | GO:0070011 | peptidase activity, acting on L-amino acid peptides | None | Extended |
| BP | GO:0071704 | organic substance metabolic process | None | Extended |
| MF | GO:0097159 | organic cyclic compound binding | None | Extended |
| MF | GO:0097367 | carbohydrate derivative binding | None | Extended |
| MF | GO:0140096 | catalytic activity, acting on a protein | None | Extended |
| MF | GO:1901265 | nucleoside phosphate binding | None | Extended |
| MF | GO:1901363 | heterocyclic compound binding | None | Extended |
| BP | GO:1901564 | organonitrogen compound metabolic process | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003916 | DNA topoisomerase activity | IEP | Predicted GO |
| MF | GO:0003968 | RNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
| CC | GO:0005622 | intracellular | IEP | Predicted GO |
| BP | GO:0006265 | DNA topological change | IEP | Predicted GO |
| BP | GO:0006643 | membrane lipid metabolic process | IEP | Predicted GO |
| BP | GO:0006664 | glycolipid metabolic process | IEP | Predicted GO |
| MF | GO:0008483 | transaminase activity | IEP | Predicted GO |
| BP | GO:0008654 | phospholipid biosynthetic process | IEP | Predicted GO |
| MF | GO:0008759 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity | IEP | Predicted GO |
| BP | GO:0009245 | lipid A biosynthetic process | IEP | Predicted GO |
| BP | GO:0009247 | glycolipid biosynthetic process | IEP | Predicted GO |
| BP | GO:0009311 | oligosaccharide metabolic process | IEP | Predicted GO |
| BP | GO:0009312 | oligosaccharide biosynthetic process | IEP | Predicted GO |
| MF | GO:0016769 | transferase activity, transferring nitrogenous groups | IEP | Predicted GO |
| MF | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor | IEP | Predicted GO |
| MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
| MF | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | IEP | Predicted GO |
| MF | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | IEP | Predicted GO |
| MF | GO:0019213 | deacetylase activity | IEP | Predicted GO |
| MF | GO:0034062 | 5'-3' RNA polymerase activity | IEP | Predicted GO |
| BP | GO:0046467 | membrane lipid biosynthetic process | IEP | Predicted GO |
| BP | GO:0046493 | lipid A metabolic process | IEP | Predicted GO |
| MF | GO:0051082 | unfolded protein binding | IEP | Predicted GO |
| BP | GO:0071103 | DNA conformation change | IEP | Predicted GO |
| MF | GO:0097747 | RNA polymerase activity | IEP | Predicted GO |
| MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
| BP | GO:1901269 | lipooligosaccharide metabolic process | IEP | Predicted GO |
| BP | GO:1901271 | lipooligosaccharide biosynthetic process | IEP | Predicted GO |
| BP | GO:1903509 | liposaccharide metabolic process | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR008269 | Lon_proteolytic | 891 | 1072 |
| IPR003111 | Lon_substr-bd | 182 | 415 |
| IPR003959 | ATPase_AAA_core | 576 | 713 |
