evm.model.contig_3414.2

Description : (at3g03300 : 120.0) Encodes a Dicer-like protein that functions in the antiviral silencing response in turnip-crinkle virus-infected plants but not in TMV or CMV-strain-Y-infected plants. Involved in the production of ta-siRNAs. Partially antagonizes the production of miRNAs by DCL1. Substitutes for DCL4 to produce viral siRNA when DCL4 is missing or inhibited. Able to produce siRNAs but not miRNAs.; dicer-like 2 (DCL2); FUNCTIONS IN: in 7 functions; INVOLVED IN: defense response to virus, maintenance of DNA methylation, production of ta-siRNAs involved in RNA interference; LOCATED IN: intracellular; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), Double-stranded RNA-binding (InterPro:IPR001159), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Ribonuclease III (InterPro:IPR000999), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Dicer double-stranded RNA-binding fold (InterPro:IPR005034), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: dicer-like 4 (TAIR:AT5G20320.1). & (reliability: 240.0) & (original description: no original description)

Gene families : OG_42_0000292 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000292_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Porphyridium release: evm.model.contig_3414.2
Cluster	HCCA clusters: Cluster_6

Target	Alias	Description	ECC score	Gene Family Method
At1g01040	No alias	Dicer-like 1 [Source:UniProtKB/TrEMBL;Acc:F4HQG6]	0.01	Orthogroups_2024-Update
Bradi5g15337	No alias	dicer-like 4	0.01	Orthogroups_2024-Update
Kfl00265_0060	kfl00265_0060_v1.1	(at1g01040 : 525.0) Encodes a Dicer homolog. Dicer is a...	0.02	Orthogroups_2024-Update
Potri.011G086700	No alias	RNAse THREE-like protein 2	0.02	Orthogroups_2024-Update
Seita.9G179100.1	No alias	endoribonuclease (DCL2) of transacting siRNA pathway	0.01	Orthogroups_2024-Update
Sopen08g021150	No alias	Ribonuclease III domain	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	None	Extended
MF	GO:0004521	endoribonuclease activity	None	Extended
MF	GO:0004525	ribonuclease III activity	IEA	InterProScan predictions
MF	GO:0004540	ribonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006396	RNA processing	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	None	Extended
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000097	sulfur amino acid biosynthetic process	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0000726	non-recombinational repair	IEP	Predicted GO
MF	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IEP	Predicted GO
MF	GO:0004659	prenyltransferase activity	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
CC	GO:0005666	RNA polymerase III complex	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006303	double-strand break repair via nonhomologous end joining	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006555	methionine metabolic process	IEP	Predicted GO
MF	GO:0008172	S-methyltransferase activity	IEP	Predicted GO
CC	GO:0008250	oligosaccharyltransferase complex	IEP	Predicted GO
MF	GO:0008318	protein prenyltransferase activity	IEP	Predicted GO
MF	GO:0008705	methionine synthase activity	IEP	Predicted GO
BP	GO:0009086	methionine biosynthetic process	IEP	Predicted GO
MF	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity	IEP	Predicted GO
MF	GO:0017069	snRNA binding	IEP	Predicted GO
MF	GO:0017070	U6 snRNA binding	IEP	Predicted GO
BP	GO:0018342	protein prenylation	IEP	Predicted GO
MF	GO:0030623	U5 snRNA binding	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
MF	GO:0031419	cobalamin binding	IEP	Predicted GO
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
BP	GO:0097354	prenylation	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000999	RNase_III_dom	1583	1673
IPR000999	RNase_III_dom	1386	1489
IPR011545	DEAD/DEAH_box_helicase_dom	40	418
IPR001650	Helicase_C	689	743

External Links

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evm.model.contig_3414.2

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation