evm.model.contig_435.7

Description : (at2g34660 : 743.0) encodes a multidrug resistance-associated protein that is MgATP-energized glutathione S-conjugate pump. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.; multidrug resistance-associated protein 2 (MRP2); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 1 (TAIR:AT1G30400.2). & (q6yuu5|mdr_orysa : 206.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 1486.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Porphyridium release: evm.model.contig_435.7
Cluster	HCCA clusters: Cluster_59

Target	Alias	Description	ECC score	Gene Family Method
94	No alias	multidrug resistance-associated protein 12	0.02	Orthogroups_2024-Update
Bradi1g37840	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
Bradi1g48697	No alias	multidrug resistance-associated protein 14	0.03	Orthogroups_2024-Update
Glyma.18G079600	No alias	multidrug resistance-associated protein 3	0.02	Orthogroups_2024-Update
LOC_Os05g10730	No alias	ABC transporter, ATP-binding protein, putative, expressed	0.02	Orthogroups_2024-Update
MA_42556g0010	No alias	(at3g60160 : 1303.0) member of MRP subfamily; multidrug...	0.02	Orthogroups_2024-Update
Mp5g06790.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Sopen11g025470	No alias	ABC transporter	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
BP	GO:0007062	sister chromatid cohesion	IEP	Predicted GO
BP	GO:0007064	mitotic sister chromatid cohesion	IEP	Predicted GO
MF	GO:0008289	lipid binding	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	IEP	Predicted GO
BP	GO:0022402	cell cycle process	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
CC	GO:0031390	Ctf18 RFC-like complex	IEP	Predicted GO
MF	GO:0035091	phosphatidylinositol binding	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	542	678
IPR003439	ABC_transporter-like	1203	1351
IPR011527	ABC1_TM_dom	187	451
IPR011527	ABC1_TM_dom	863	1118

External Links

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evm.model.contig_435.7

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation