evm.model.contig_4398.1

Description : (at1g52500 : 146.0) Encodes one of the splice variants of Arabidopsis thaliana MutM homolog. Encodes a formamidopyrimidine-DNA glycosylase that has abasic lyase activity and is able to nick double- stranded oligonucleotides containing 8-oxo-7,8-dihydroguanine (8-oxoG) in vitro.; MUTM homolog-1 (MMH-1); CONTAINS InterPro DOMAIN/s: Ribosomal protein S13-like, H2TH (InterPro:IPR010979), DNA glycosylase/AP lyase, H2TH DNA-binding (InterPro:IPR015886), DNA glycosylase/AP lyase, catalytic domain (InterPro:IPR012319), DNA glycosylase/AP lyase (InterPro:IPR000191); Has 11102 Blast hits to 10156 proteins in 2240 species: Archae - 10; Bacteria - 5065; Metazoa - 1812; Fungi - 570; Plants - 321; Viruses - 42; Other Eukaryotes - 3282 (source: NCBI BLink). & (reliability: 292.0) & (original description: no original description)

Gene families : OG_42_0004977 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004977_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Porphyridium release: evm.model.contig_4398.1
Cluster	HCCA clusters: Cluster_84

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	InterProScan predictions
BP	GO:0006289	nucleotide-excision repair	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	InterProScan predictions
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	None	Extended
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEA	InterProScan predictions
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Predicted GO
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Predicted GO
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Predicted GO
MF	GO:0004784	superoxide dismutase activity	IEP	Predicted GO
MF	GO:0004843	thiol-dependent ubiquitin-specific protease activity	IEP	Predicted GO
MF	GO:0005096	GTPase activator activity	IEP	Predicted GO
CC	GO:0005680	anaphase-promoting complex	IEP	Predicted GO
CC	GO:0005787	signal peptidase complex	IEP	Predicted GO
BP	GO:0006465	signal peptide processing	IEP	Predicted GO
BP	GO:0006541	glutamine metabolic process	IEP	Predicted GO
BP	GO:0006542	glutamine biosynthetic process	IEP	Predicted GO
BP	GO:0006553	lysine metabolic process	IEP	Predicted GO
BP	GO:0006771	riboflavin metabolic process	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006888	ER to Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0007088	regulation of mitotic nuclear division	IEP	Predicted GO
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Predicted GO
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Predicted GO
MF	GO:0008837	diaminopimelate epimerase activity	IEP	Predicted GO
BP	GO:0009064	glutamine family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009085	lysine biosynthetic process	IEP	Predicted GO
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Predicted GO
BP	GO:0009231	riboflavin biosynthetic process	IEP	Predicted GO
CC	GO:0009349	riboflavin synthase complex	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
BP	GO:0010564	regulation of cell cycle process	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Predicted GO
BP	GO:0016053	organic acid biosynthetic process	IEP	Predicted GO
MF	GO:0016211	ammonia ligase activity	IEP	Predicted GO
BP	GO:0016485	protein processing	IEP	Predicted GO
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Predicted GO
MF	GO:0016854	racemase and epimerase activity	IEP	Predicted GO
MF	GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives	IEP	Predicted GO
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Predicted GO
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Predicted GO
BP	GO:0032006	regulation of TOR signaling	IEP	Predicted GO
BP	GO:0033043	regulation of organelle organization	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Predicted GO
BP	GO:0033047	regulation of mitotic sister chromatid segregation	IEP	Predicted GO
MF	GO:0036361	racemase activity, acting on amino acids and derivatives	IEP	Predicted GO
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0043248	proteasome assembly	IEP	Predicted GO
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Predicted GO
BP	GO:0046451	diaminopimelate metabolic process	IEP	Predicted GO
MF	GO:0047661	amino-acid racemase activity	IEP	Predicted GO
BP	GO:0051128	regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051783	regulation of nuclear division	IEP	Predicted GO
BP	GO:0051983	regulation of chromosome segregation	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Predicted GO
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Predicted GO
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Predicted GO
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Predicted GO
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
BP	GO:1902531	regulation of intracellular signal transduction	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
BP	GO:1905818	regulation of chromosome separation	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR012319	FPG_cat	1	153
IPR015886	DNA_glyclase/AP_lyase_DNA-bd	169	252

External Links

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evm.model.contig_4398.1

Expression Profile

Co-expression Networks

Functional Annotation