evm.model.contig_4449.8


Description : (at2g31660 : 404.0) SAD2 (super sensitive to ABA and drought 2) encodes an importin beta-domain family protein likely to be involved in nuclear transport in ABA signaling. Subcellular localization of GFP-tagged SAD2 showed a predominantly nuclear localization, consistent with a role for SAD2 in nuclear transport. Mutation of SAD2 in Arabidopsis alters abscisic acid sensitivity. SAD2 was ubiquitously expressed at low levels in all tissues except flowers. SAD2 expression was not induced by ABA or stress. Loss of function mutations in SAD2 exhibit increased tolerance for UV stress, increased production of UV protective secondary metabolites and suppression of nuclear localization of MYB4 (a repressor of UV stress response genes).; SUPER SENSITIVE TO ABA AND DROUGHT2 (SAD2); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: protein import into nucleus, docking, protein import into nucleus; LOCATED IN: nucleus, nuclear pore, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), Exportin/Importin, Cse1-like (InterPro:IPR013713); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT3G59020.1); Has 3689 Blast hits to 2792 proteins in 293 species: Archae - 3; Bacteria - 183; Metazoa - 1271; Fungi - 834; Plants - 368; Viruses - 60; Other Eukaryotes - 970 (source: NCBI BLink). & (reliability: 808.0) & (original description: no original description)


Gene families : OG_42_0003831 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003831_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_4449.8
Cluster HCCA clusters: Cluster_56

Target Alias Description ECC score Gene Family Method Actions
evm.model.tig00000217.11 No alias (at3g59020 : 672.0) ARM repeat superfamily protein;... 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006886 intracellular protein transport IEA InterProScan predictions
MF GO:0008536 Ran GTPase binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004180 carboxypeptidase activity IEP Predicted GO
MF GO:0004181 metallocarboxypeptidase activity IEP Predicted GO
MF GO:0005506 iron ion binding IEP Predicted GO
BP GO:0006338 chromatin remodeling IEP Predicted GO
BP GO:0006629 lipid metabolic process IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
BP GO:0008610 lipid biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001494 Importin-beta_N 27 102
IPR013713 XPO2_central 180 453
No external refs found!