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- evm.model.contig_4455.3
evm.model.contig_4455.3
Description : (at5g58230 : 470.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 940.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Porphyridium release: evm.model.contig_4455.3 | |
Cluster | HCCA clusters: Cluster_8 | |
Expression Context Conservation (ECC)
Target | Alias | Description | ECC score | Gene Family Method | Actions |
233646 | No alias | Transducin/WD40 repeat-like superfamily protein | 0.03 | Orthogroups_2024-Update | |
Brara.I01007.1 | No alias | component *(CAF1c/MSI) of CAF1 histone chaperone complex... | 0.02 | Orthogroups_2024-Update | |
Kfl00523_0070 | kfl00523_0070_v1.1 | (at5g58230 : 676.0) Encodes a WD-40 repeat containing... | 0.02 | Orthogroups_2024-Update | |
Solyc01g104510 | No alias | WD-40 repeat protein | 0.03 | Orthogroups_2024-Update | |
evm.model.tig00000808.15 | No alias | (at5g58230 : 455.0) Encodes a WD-40 repeat containing... | 0.01 | Orthogroups_2024-Update | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0005488 | binding | None | Extended |
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
MF | GO:0003676 | nucleic acid binding | IEP | Predicted GO |
MF | GO:0003723 | RNA binding | IEP | Predicted GO |
MF | GO:0003746 | translation elongation factor activity | IEP | Predicted GO |
MF | GO:0003779 | actin binding | IEP | Predicted GO |
MF | GO:0003922 | GMP synthase (glutamine-hydrolyzing) activity | IEP | Predicted GO |
MF | GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity | IEP | Predicted GO |
MF | GO:0004812 | aminoacyl-tRNA ligase activity | IEP | Predicted GO |
MF | GO:0005524 | ATP binding | IEP | Predicted GO |
CC | GO:0005741 | mitochondrial outer membrane | IEP | Predicted GO |
CC | GO:0005852 | eukaryotic translation initiation factor 3 complex | IEP | Predicted GO |
BP | GO:0006177 | GMP biosynthetic process | IEP | Predicted GO |
BP | GO:0006399 | tRNA metabolic process | IEP | Predicted GO |
BP | GO:0006414 | translational elongation | IEP | Predicted GO |
BP | GO:0006418 | tRNA aminoacylation for protein translation | IEP | Predicted GO |
MF | GO:0008135 | translation factor activity, RNA binding | IEP | Predicted GO |
MF | GO:0008144 | drug binding | IEP | Predicted GO |
MF | GO:0008289 | lipid binding | IEP | Predicted GO |
MF | GO:0008536 | Ran GTPase binding | IEP | Predicted GO |
BP | GO:0009163 | nucleoside biosynthetic process | IEP | Predicted GO |
MF | GO:0016874 | ligase activity | IEP | Predicted GO |
MF | GO:0016875 | ligase activity, forming carbon-oxygen bonds | IEP | Predicted GO |
MF | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor | IEP | Predicted GO |
MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
CC | GO:0019867 | outer membrane | IEP | Predicted GO |
MF | GO:0030554 | adenyl nucleotide binding | IEP | Predicted GO |
CC | GO:0031968 | organelle outer membrane | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032559 | adenyl ribonucleotide binding | IEP | Predicted GO |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
BP | GO:0042451 | purine nucleoside biosynthetic process | IEP | Predicted GO |
BP | GO:0042455 | ribonucleoside biosynthetic process | IEP | Predicted GO |
BP | GO:0043038 | amino acid activation | IEP | Predicted GO |
BP | GO:0043039 | tRNA aminoacylation | IEP | Predicted GO |
MF | GO:0043167 | ion binding | IEP | Predicted GO |
MF | GO:0043168 | anion binding | IEP | Predicted GO |
BP | GO:0046037 | GMP metabolic process | IEP | Predicted GO |
BP | GO:0046129 | purine ribonucleoside biosynthetic process | IEP | Predicted GO |
MF | GO:0070008 | serine-type exopeptidase activity | IEP | Predicted GO |
MF | GO:0097159 | organic cyclic compound binding | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
CC | GO:0098588 | bounding membrane of organelle | IEP | Predicted GO |
CC | GO:0098805 | whole membrane | IEP | Predicted GO |
MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
MF | GO:0140101 | catalytic activity, acting on a tRNA | IEP | Predicted GO |
BP | GO:1901070 | guanosine-containing compound biosynthetic process | IEP | Predicted GO |
MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
MF | GO:1901363 | heterocyclic compound binding | IEP | Predicted GO |
BP | GO:1901659 | glycosyl compound biosynthetic process | IEP | Predicted GO |