evm.model.contig_4455.3


Description : (at5g58230 : 470.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 940.0) & (original description: no original description)


Gene families : OG_42_0002428 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002428_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_4455.3
Cluster HCCA clusters: Cluster_8

Target Alias Description ECC score Gene Family Method Actions
233646 No alias Transducin/WD40 repeat-like superfamily protein 0.03 Orthogroups_2024-Update
Brara.I01007.1 No alias component *(CAF1c/MSI) of CAF1 histone chaperone complex... 0.02 Orthogroups_2024-Update
Kfl00523_0070 kfl00523_0070_v1.1 (at5g58230 : 676.0) Encodes a WD-40 repeat containing... 0.02 Orthogroups_2024-Update
Solyc01g104510 No alias WD-40 repeat protein 0.03 Orthogroups_2024-Update
evm.model.tig00000808.15 No alias (at5g58230 : 455.0) Encodes a WD-40 repeat containing... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003779 actin binding IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005741 mitochondrial outer membrane IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
MF GO:0008536 Ran GTPase binding IEP Predicted GO
BP GO:0009163 nucleoside biosynthetic process IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
CC GO:0019867 outer membrane IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
CC GO:0031968 organelle outer membrane IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042451 purine nucleoside biosynthetic process IEP Predicted GO
BP GO:0042455 ribonucleoside biosynthetic process IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046129 purine ribonucleoside biosynthetic process IEP Predicted GO
MF GO:0070008 serine-type exopeptidase activity IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
CC GO:0098588 bounding membrane of organelle IEP Predicted GO
CC GO:0098805 whole membrane IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901659 glycosyl compound biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 282 320
IPR001680 WD40_repeat 236 273
IPR001680 WD40_repeat 329 363
IPR001680 WD40_repeat 385 420
IPR022052 Histone-bd_RBBP4_N 16 85
No external refs found!