evm.model.contig_450.8


Description : (at3g54960 : 232.0) Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). Neither AtIRE1-2 nor AtbZIP60 appear to be required for this response.; PDI-like 1-3 (PDIL1-3); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to endoplasmic reticulum stress; LOCATED IN: endoplasmic reticulum, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Protein disulphide isomerase (InterPro:IPR005792), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 1-4 (TAIR:AT5G60640.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (p29828|pdi_medsa : 215.0) Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) - Medicago sativa (Alfalfa) & (reliability: 464.0) & (original description: no original description)


Gene families : OG_42_0002283 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002283_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_450.8
Cluster HCCA clusters: Cluster_59

Target Alias Description ECC score Gene Family Method Actions
At1g77510 No alias Protein disulfide isomerase-like 1-2... 0.02 Orthogroups_2024-Update
Brara.G01064.1 No alias protein disulfide isomerase *(PDI-L) & EC_5.3... 0.01 Orthogroups_2024-Update
Brara.G03521.1 No alias protein disulfide isomerase *(PDI-L) & EC_5.3... 0.02 Orthogroups_2024-Update
GRMZM2G163421 No alias PDI-like 1-2 0.01 Orthogroups_2024-Update
Mp3g15650.1 No alias Protein disulfide-isomerase OS=Ricinus communis... 0.01 Orthogroups_2024-Update
Solyc06g005940 No alias Protein disulfide-isomerase (AHRD V3.3 *** K4C376_SOLLC) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0045454 cell redox homeostasis IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEP Predicted GO
MF GO:0003779 actin binding IEP Predicted GO
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0007010 cytoskeleton organization IEP Predicted GO
BP GO:0008156 negative regulation of DNA replication IEP Predicted GO
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEP Predicted GO
BP GO:0009890 negative regulation of biosynthetic process IEP Predicted GO
BP GO:0009892 negative regulation of metabolic process IEP Predicted GO
BP GO:0010558 negative regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010605 negative regulation of macromolecule metabolic process IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016877 ligase activity, forming carbon-sulfur bonds IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0031324 negative regulation of cellular metabolic process IEP Predicted GO
BP GO:0031327 negative regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0032993 protein-DNA complex IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0045005 DNA-dependent DNA replication maintenance of fidelity IEP Predicted GO
BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0048478 replication fork protection IEP Predicted GO
BP GO:0051052 regulation of DNA metabolic process IEP Predicted GO
BP GO:0051053 negative regulation of DNA metabolic process IEP Predicted GO
BP GO:0051172 negative regulation of nitrogen compound metabolic process IEP Predicted GO
MF GO:0070008 serine-type exopeptidase activity IEP Predicted GO
BP GO:0090329 regulation of DNA-dependent DNA replication IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:2000104 negative regulation of DNA-dependent DNA replication IEP Predicted GO
BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 372 473
IPR013766 Thioredoxin_domain 28 127
No external refs found!