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  5. evm.model.contig_4509.2

evm.model.contig_4509.2


Description : (at3g01120 : 171.0) encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.; METHIONINE OVERACCUMULATION 1 (MTO1); FUNCTIONS IN: cystathionine gamma-synthase activity; INVOLVED IN: methionine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT1G33320.1); Has 21364 Blast hits to 20702 proteins in 2452 species: Archae - 220; Bacteria - 11705; Metazoa - 241; Fungi - 842; Plants - 284; Viruses - 13; Other Eukaryotes - 8059 (source: NCBI BLink). & (reliability: 342.0) & (original description: no original description)


Gene families : OG_42_0001443 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001443_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_4509.2
Cluster HCCA clusters: Cluster_8

Target Alias Description ECC score Gene Family Method Actions
Glyma.19G132000 No alias cystathionine beta-lyase 0.01 Orthogroups_2024-Update
LOC_Os06g07860 No alias cystathionine gamma-synthase, putative, expressed 0.02 Orthogroups_2024-Update
Mp1g04580.1 No alias cystathionine beta-lyase 0.01 Orthogroups_2024-Update
Potri.017G086500 No alias Pyridoxal phosphate (PLP)-dependent transferases... 0.01 Orthogroups_2024-Update
Sobic.001G357300.3 No alias cystathionine gamma-synthase & EC_2.5 transferase... 0.01 Orthogroups_2024-Update
evm.model.tig00001049.7 No alias (at3g57050 : 159.0) Encodes second enzyme in the... 0.04 Orthogroups_2024-Update
evm.model.tig00021350.37 No alias (at3g01120 : 447.0) encodes a cystathionine... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0030170 pyridoxal phosphate binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000049 tRNA binding IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0001522 pseudouridine synthesis IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003852 2-isopropylmalate synthase activity IEP Predicted GO
MF GO:0003855 3-dehydroquinate dehydratase activity IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IEP Predicted GO
MF GO:0004664 prephenate dehydratase activity IEP Predicted GO
MF GO:0004764 shikimate 3-dehydrogenase (NADP+) activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0004826 phenylalanine-tRNA ligase activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005737 cytoplasm IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006188 IMP biosynthetic process IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006432 phenylalanyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006551 leucine metabolic process IEP Predicted GO
BP GO:0006558 L-phenylalanine metabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
BP GO:0009081 branched-chain amino acid metabolic process IEP Predicted GO
BP GO:0009082 branched-chain amino acid biosynthetic process IEP Predicted GO
BP GO:0009094 L-phenylalanine biosynthetic process IEP Predicted GO
BP GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway IEP Predicted GO
BP GO:0009098 leucine biosynthetic process IEP Predicted GO
BP GO:0009123 nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009163 nucleoside biosynthetic process IEP Predicted GO
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009451 RNA modification IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016835 carbon-oxygen lyase activity IEP Predicted GO
MF GO:0016836 hydro-lyase activity IEP Predicted GO
MF GO:0016840 carbon-nitrogen lyase activity IEP Predicted GO
MF GO:0016842 amidine-lyase activity IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor IEP Predicted GO
MF GO:0017056 structural constituent of nuclear pore IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
MF GO:0030515 snoRNA binding IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
CC GO:0030688 preribosome, small subunit precursor IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
BP GO:0042254 ribosome biogenesis IEP Predicted GO
BP GO:0042451 purine nucleoside biosynthetic process IEP Predicted GO
BP GO:0042455 ribonucleoside biosynthetic process IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046040 IMP metabolic process IEP Predicted GO
BP GO:0046129 purine ribonucleoside biosynthetic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
MF GO:0070008 serine-type exopeptidase activity IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901607 alpha-amino acid biosynthetic process IEP Predicted GO
BP GO:1901659 glycosyl compound biosynthetic process IEP Predicted GO
BP GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process IEP Predicted GO
BP GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000277 Cys/Met-Metab_PyrdxlP-dep_enz 126 498
No external refs found!